In the raiA ncRNA structure that we recently determined, we identified a junction strand (B) that mimics both the GAAA-tetraloop (A) AND the D-loop/T-loop interaction motif (C) - how cool is that?

Find out more:
https://doi.org/10.1016/j.jmb.2024.168833

#RNA #research #science #Structure #structuralbiology #cryoEM #junction #tetraloop #strand #motif #Dloop #Tloop #GAAA #GNRA #raiA

Cryo-EM Structure of raiA ncRNA From Clostridium Reveals a New RNA 3D Fold

Advancements in genome-wide sequence analysis have led to the discovery of numerous novel bacterial non-coding RNAs (ncRNAs). These ncRNAs have been c…