Mastodawn

Moritz 🌊🌊🌊🌊🌊🌊🌊🌊Ukraine Supporter May 11, 2025

Engineered T-cells that express both #CARs and #TCRs can better distinguish between cancerous and healthy tissues

Engineered T-cells that expres...

Bluesky

Bluesky Social

Brett Callow Jul 12, 2023

Pension Benefit Information has reported a #MOVEit-related breach in relation to an unspecified client which affected >300k people.

#PBI's clients include orgs which have already disclosed being impacted: #CapPERS, #CalSTRS, #TIAA and #TCRS.

Stats -

Organizations impacted: 280
Individuals impacted: 18,139,588

https://apps.web.maine.gov/online/aeviewer/ME/40/14efac97-4a7c-4322-98eb-2e953884eb58.shtml

Office of the Maine AG: Consumer Protection: Privacy, Identity Theft and Data Security Breaches

Brett Callow Jun 29, 2023

Tennessee Consolidated Retirement System was impacted by #MOVEit with the breach impacting 171,836 retirees and/or their beneficiaries.

Like #CalPERS and #CalSTRS, #TCRS was breached via service provider #PBI which works with multiple other pension plans. How many, if any, more were impacted is not yet clear.

There are now 141 known MOVEit victims, with the related breaches impacting the info of 15,659,731 people. Note that this number is based only on the disclosures of the 10 orgs which have actually confirmed the number of people affected.

https://treasury.tn.gov/Portals/0/Documents/Retirement/PBIIncidentFAQ.pdf

Brett Callow Jun 22, 2023

#PBI Research Services - the company which exposed #CalPERS' data via #MOVEit - works with multiple other public pensions including #NVPERS, #NJDPB, and #TCRS.

DiverseTCR Feb 9, 2023

It's almost become #fancy to do #scTCRseq and make conclusions on #specificity ...we are no where close to it...read this carefully. #Amazing #TCRs https://www.nature.com/articles/s41577-023-00835-3

Can we predict T cell specificity with digital biology and machine learning? - Nature Reviews Immunology

Koohy and co-workers discuss how we must turn to machine-learning approaches to define the antigen specificity of the many millions of possible T cell receptors. They review the models and methods currently being used to predict cognate antigens for orphan T cell receptors.

Nature

DiverseTCR Jan 18, 2023

This is an essential paper if you are interested in #TCRs and #autoimmunity
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RT @andimscience
Our paper now out in @PNASNews : Measures of epitope binding degeneracy from T cell receptor repertoires https://www.pnas.org/doi/10.1073/pnas.2213264120
https://twitter.com/andimscience/status/1615675147540918274

DiverseTCR Dec 20, 2022