Daniel CaronJul 17, 2023

Cool computational method for separating γδ #Tcells by #rna #sequencing
Rather than relying on paired #TCRseq or #CITEseq, they calculate module scores of TCR constant and variable region gene expression

https://doi.org/10.1093/jleuko/qiad069

Human γδ T cell Identification from Single-cell RNA Sequencing Datasets by Modular TCR Expression

Analysis method, based on TCR gene module scores, to identify γδ T cells from 5'-end scRNA-seq datasets.

OUP Academic
DiverseTCRDec 6, 2022
Just finished sequencing #10million #TCRs from two different #human #organs, #mansucript #written and ready for #submission soon. #scRNAseq #TCRseq #immuneorganoids..#preprint on its way! #human #immunology