'Boosting pancreatic cancer chemotherapy by disrupting nerve–cancer crosstalk' - an Acta Materia Medica article on #ScienceOpen:

🔗 https://www.scienceopen.com/hosted-document?doi=10.15212/AMM-2024-0092

🖇️ #CancerBiology #Pharmaceutics #Biochemistry #PancreaticCancer

Unlike many other drugs that treat viruses, Sovaldi does not suppress hepatitis C, a virus that kills roughly 250,000 people around the world each year. It cures it.

“Normally you have a virus, and your body fights it off or your body fights it to a standstill and you just have it forever, basically, and hope it remains dormant more or less,” Laufer said. “The holy grail for every virologist is to find a way to drain the viral reservoir, and Sovaldi does this. You take one pill of Sovaldi a day for 12 weeks and then you don’t have hepatitis C anymore.”

The problem is that those pills are under patent, and they cost $1,000 per pill.

“Literally, if you have $84,000 then hepatitis C is not your problem anymore,” Laufer said. “But given that there are other methodologies for managing hepatitis C that are not curing it and that are cheaper, insurance typically will not cover [Sovaldi]. And so we’ve got this incredible technology and it’s sitting on the shelf except for people who are ridiculously wealthy.”

So Four Thieves Vinegar Collective set out to teach people how to make their own version of Sovaldi. Chemists at the collective thought the DIY version would cost about $300 for the entire course of medication, or about $3.57 per pill. But they were wrong.

“It’s actually just a little under $70 (83 cents per pill), which just kind of blew my mind when they finally showed me the results,” Laufer said. “I was like, can we do the math here again?”

The above lines were written for paid subscribers and are excerpt from #404Media https://www.404media.co/right-to-repair-for-your-body-the-rise-of-diy-pirated-medicine/ @law

#pharma #pharmacy #pharmaceutics #Hepatitis #HepatitisC #cure #illness #health #medicine #DIY #pirating #counterfeit #free #patents #research #money #law #FederalLaw #intellectualProperty

The #US faces shortages of essential drugs, including cancer treatments, due to a broken #health system. The solutions at hand are inadequate, since for-profit drug companies prioritise profits over #generics.

How about a public #pharmaceutics option to produce and distribute vital medicines affordably? This approach has succeeded in other countries. #PublicInvestment in drug manufacturing infrastructure could create jobs and rebalance the power.

#bigpharma
https://znetwork.org/znetarticle/public-pharma-is-the-best-solution-to-the-ongoing-problem-of-drug-shortages/

Europe 🇪🇺 must make its own medicines and rely less on China 🇨🇳 and India 🇮🇳. The @EPPGroup is looking at the @EU_Commission - we urgently need new rules concerning #pharmaceutics.

We have no time to waste.

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🐦🔗: https://n.respublicae.eu/peterliese/status/1617573409994555405