🧠🚓 New paper on #microglia depletion: #CSF1R inhibition with #PLX5622 is not microglia-specific, it also depletes long-lived peripheral #macrophage populations. Could become important for interpreting #microglial #depletion experiments: Phenotypes after depletion or recovery may reflect broader macrophage niche perturbation, not microglia alone:

📄 https://doi.org/10.1016/j.celrep.2026.117411

#Neuroscience #Neuroimmunology