This brief highlights a mechanistic target in an autoimmune brain disorder, offering a concise point of relevance for clinicians focused on neuropsychiatric presentations. Understanding the NMDA receptor-centered pathophysiology informs caseload awareness where psychiatric symptoms intersect with neuroimmune processes, aiding differential thinking and collaboration with neuroscience colleagues.

Article Title: New drug target discovered for devastating “brain on fire” disease

Link to Science Daily Mind-Brain News: https://www dot sciencedaily dot com/releases/2026/02/260225081150 dot htm

#brainhealth #neuroimmunology #NMDAreceptors #neuropsychiatry #autoinflammatorydisease

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Job Alert

Postdoktorand/ Postdoktorandin (m/w/d) Forschungszentrum für Regenerative Therapien  

Deadline: 2026-03-12
Location: Germany - Dresden  

https://www.academiceurope.com/ads/postdoktorand-postdoktorandin-m-w-d-forschungszentrum-fur-regenerative-therapien/

#hiring #Postdoc #LifeSciences #bioinformatics #medicine #Neuroimmunology #biochemistry #neuroscience

Too sick to socialize: How the brain and immune system promote staying in bed | MIT News

“I just can’t make it tonight. You have fun without me.” Across much of the animal kingdom, when…
#NewsBeep #News #Headlines #cytokines #dorsalraphenucleus(DRN) #GloriaChoi #IL-1R1 #IL-1β #Latvia #LiuYang #LV #MITBCS #MITPicowerInstitute #neuroimmuneinteractions #Neuroimmunology #sicknessbehavior #socialisolation
https://www.newsbeep.com/299645/

ERC-funded 3-year postdoc position with Michael Dolan in Dublin, Ireland, on neuroimunology and genomics. To apply, write an email to Michael.

https://dolanlab-tcd.com/

#PhDJobs #neuroscience #neuroimmunology #immunology #genomics

Scientists have uncovered a major breakthrough in multiple sclerosis (MS) research. By activating a single gene called EGR-1, researchers successfully restored immune balance and relieved MS-like symptoms in mice. This discovery offers fresh hope for millions affected by this chronic disease where the immune system attacks the protective covering of nerves.

EGR-1 plays a crucial role in regulating immune responses and reducing the inflammation that damages nerve cells. When researchers switched on this gene, they observed a remarkable reduction in inflammation and significant improvement in neurological function. The treated mice regained mobility and showed decreased signs of nerve damage, a result that could transform future MS therapies.

Unlike current treatments that mainly focus on slowing disease progression or managing symptoms, targeting EGR-1 addresses the root cause by reprogramming immune cells to protect rather than attack the nervous system. Scientists believe this approach could one day be adapted into gene therapy for humans, offering long-term relief or even reversing certain aspects of the disease.

While more research and clinical trials are essential to confirm safety and effectiveness in humans, this study marks a promising step toward groundbreaking therapies that could change the outlook for people with multiple sclerosis. It’s a compelling example of how genetics may hold the key to curing complex autoimmune disorders.

Core breakthrough & research
#MedicalBreakthrough #Genetics #Immunology #LifeSciences #FutureOfMedicine

Disease focus
#MultipleSclerosis #MSResearch #AutoimmuneDisease #NeuroScience #NeuroImmunology

Therapy specifics & hope
#GeneTherapy #EGR1 #TargetedTreatment #InnovativeMedicine #HopeForPatients

--Postdoctoral Fellowship in Structural Neurophysiology at CSHL—
Cold Spring Harbor Laboratory @Lab_FURUKAWA

Join us to conduct cutting-edge science and advance your career. #cryo-EM #electrophysiology #neuroscience #neuroimmunology

See the full job description on jobRxiv: https://jobrxiv.org/job/cold-spring-harbor-laboratory-27778-postdoctoral-fellowship-i...
https://jobrxiv.org/job/cold-spring-harbor-laboratory-27778-postdoctoral-fellowship-in-structural-neurophysiology-at-cshl/?fsp_sid=1530

--Postdoctoral Fellowship in Structural Neurophysiology at CSHL—
Cold Spring Harbor Laboratory @Lab_FURUKAWA

Join us to conduct cutting-edge science and advance your career. #cryo-EM #electrophysiology #neuroscience #neuroimmunology

See the full job description on jobRxiv: https://jobrxiv.org/job/cold-spring-harbor-laboratory-27778-postdoctoral-fellowship-in...
https://jobrxiv.org/job/cold-spring-harbor-laboratory-27778-postdoctoral-fellowship-in-structural-neurophysiology-at-cshl/?fsp_sid=802