U01.01.104 Pentose Phosphate Pathway: G6PD, NADPH, and Ribose-5-Phosphate

Master the Pentose Phosphate Pathway (PPP) with our U01.01.104 guide. Learn about the oxidative and non-oxidative phases, the role of G6PD, and the production of NADPH for reductive biosynthesis and glutathione reduction. Essential USMLE Step 1 biochemistry available on mymedschool.org.

mymedschool.org
U01.01.094 Universal Electron Acceptors: NAD+, NADP+, and FAD in Biochemistry

Master the "Big Three" electron acceptors in cellular metabolism with our U01.01.094 guide. Learn the key differences between NAD+ (catabolism), NADP+ (anabolism), and FAD (redox cycles). Explore their vitamin precursors, high-energy states, and high-yield board exam associations for USMLE Step 1. Available at mymedschool.org.

mymedschool.org

Keisuke Shigeta et al (Keio University School of Medicine) analyze #metabolic alterations leading to #chemoresistance in #urothelial cancer #bladdercancer: #IDH2 gain-of-function independent of #mutation is responsible for #HIF1α-dependent production of respective #gemcitabine and #CDDP competitors #dCTP and #NADPH

https://www.embopress.org/doi/10.15252/embj.2022110620