As #BirdFlu wreaks havoc in the Midwest, researchers say #vaccines offer a way out

Researchers say vaccinating poultry is crucial for reining in H5 and reducing the stress on farmers and consumers hit by high egg prices. Vaccination could also help reduce the number of infections and the threat of a pandemic.

By Brian Allnutt
April 2, 2025

Excerpt: "Spring and fall bird migrations could add to bird flu threat

"Spring and fall bird migrations could add to the H5 threat as birds congregate in areas near farms and mix with waterfowl, which are key hosts for the virus.

"In the Great Lakes region, a combination of migratory bird flyways, waste grain missed during harvest, and abundant lakes and reservoirs attracts large numbers of migrating birds—and potentially high levels of avian flu virus, says Matthew Hardy, a waterfowl ecologist and co-founder of #AgriNerds, a company that tracks bird movements to help farms prevent outbreaks.

"Hardy pointed to Darke and Mercer counties in northwest Ohio, near Dayton, as areas where some of these factors may have contributed to major outbreaks in poultry facilities in late 2024 and early 2025.

" 'There’s going to be continued outbreaks and likely mass die-offs in places where birds stage,' Hardy said, referring to the areas where birds come together and rest during migration.

"Wetland loss could make this issue worse, pushing birds closer to farms.

"Changing temperatures, weather patterns, and human activity have driven the loss of natural wetlands that waterfowl and other species depend on, Hardy said. This has brought them closer to farms as they search for food and suitable habitat. The rate of wetland loss, primarily driven by agriculture, has increased in recent years in the Upper Midwest, Grist reports.

"Cardona, with the University of Minnesota, said fall may pose a more significant threat for disease spread than spring. Birds flying north in spring often have some immunity from exposure to viruses the previous year. But those hatched in fall don’t have immunity and may be more vulnerable and likely to spread the virus, especially in the Upper Midwest.

" 'The birds are breeding and propagating up near the Arctic Circle or in colder areas … As they fly south, those birds mix and mingle and share and reassort viruses,' she said.

"Birds develop antibodies on their southward migrations, reducing the amount of virus they shed over time, Cardona said. This could explain why so many H5 outbreaks occurred in the upper part of U.S. flyways in states like Minnesota, Michigan, and the Dakotas, which also have large numbers of turkeys and laying hens that are especially susceptible to H5.

"She emphasized the difficulty of making predictions about H5.

" 'The only predictable thing about influenza is that it’s entirely unpredictable,' she said."

https://www.greatlakesnow.org/2025/04/as-bird-flu-wreaks-havoc-in-the-midwest-researchers-say-vaccines-offer-a-way-out/

#HPAINews #AvianInfluenza
#H5N1 #LPAI #HPAI #BirdFlu #HealthInformation #CDCFundingCuts

As bird flu wreaks havoc in the Midwest, researchers say vaccines offer a way out | Great Lakes Now

Great Lakes farms have become a hot spot for bird flu, killing millions of birds and raising fears of a human pandemic.

Great Lakes Now

So, this site is very simple, but it's been around for years. Visit the forum for the latest posts about #diseases and #zoonoses.

For example, I found this item, posted by one of the moderators, under the thread:
#Texas - #AvianInfluenza in mammals and livestock 2023-2025 [Click the fast forward button to get to the latest post]

"Media (City of Spur, Facebook page)
City of #SpurTexas
May 8, 2025

"Important Notice: #BirdFlu Detected in #StrayCats

"The Texas Department of State Health Services has alerted us that a strain of bird flu is affecting stray cats in the area. The symptoms can look similar to rabies, and this virus is highly contagious to humans.

"Please be cautious around stray cats. If you see a sick or unusually acting cat, DO NOT TOUCH IT. Report it to City of Spur or the appropriate authorities right away.

"Your safety is important - stay alert and help spread the word!​"

https://flutrackers.com/forum/search?searchJSON=%7B%22last%22%3A%7B%22from%22%3A%222%22%7D%2C%22view%22%3A%22topic%22%2C%22starter_only%22%3A+1%2C%22sort%22%3A%7B%22lastcontent%22%3A%22desc%22%7D%2C%22exclude_type%22%3A%5B%22vBForum_PrivateMessage%22%5D%7D

#HPAINews #AvianInfluenza
#H5N1 #LPAI #HPAITexas #HPAI #BirdFlu #HealthInformation #Parasites #HPAIResources #DiseaseResources #CDCFundingCuts

Search Result - FluTrackers News and Information

vBulletin Search

FluTrackers News and Information

#WAHIS: World Animal Health Information System

"WAHIS is the global animal health reference database of the World Organisation for Animal Health (#WOAH). WAHIS data reflects the validated information since 2005 reported by the Veterinary Services from Member and non-Member Countries and Territories on terrestrial and aquatic Listed diseases in domestic animals and wildlife, as well as on emerging #diseases and #zoonoses.

"WAHIS includes interactive mapping tools and dashboards to support data consultation, visualization and extraction of officially validated animal health data."

https://wahis.woah.org/#/home

#HPAINews #AvianInfluenza #H5N1 #Diseases #LPAI #HPAI #BirdFlu #HealthData #HealthInformation #Parasites #HPAIResources #DiseaseResources #CDCFundingCuts #WAHIS

WAHIS

Gee, Mexico is vaccinating poultry against #BirdFlu. What is the US doing? Sitting on their hands and withholding information, apparently...!

Autorización para la vacunación en zonas de escasa prevalencia de influenza aviar A H5N2

"La vacunación contra el virus de influenza aviar A H5N2, puede aplicarse únicamente en unidades de producción ubicadas en regiones identificadas como zona de escasa prevalencia, en los estados de: Coahuila, Durango, Guanajuato, Hidalgo, Jalisco, Michoacán, Morelos, Nayarit, Puebla, Querétaro y San Luis Potosí, previa autorización del Senasica."

[English version] Authorization for Vaccination
in Areas with Low Prevalence
of Avian Influenza A H5N2

"Vaccination against the avian influenza A H5N2 virus can only be applied in production units located in regions identified as a low prevalence area in the states of: Coahuila, Durango, Guanajuato,
Hidalgo, Jalisco, Michoacán, Morelos, Nayarit, Puebla, Querétaro, and San Luis Potosí, with prior authorization from Senasica"

https://www.gob.mx/senasica/acciones-y-programas/autorizacion-para-la-vacunacion-en-zonas-de-riesgo-de-influenza-aviar-h5n2

#HPAINews #BirdFlu #Mexico #AvianInfluenza #H5N2 #LPAI

Autorización para la vacunación en zonas de escasa prevalencia de influenza aviar A H5N2

.

gob.mx
Ja m'ho han llegit més d'un cop. Aquí, ben explicat, encara que es bastant llarg. #H5N1 #HPAI s'ha escampat entre les aus silvestres que l'han propagat a tots els continents (llevat Austràlia, fins ara). Però no és una creació "natural"; allò que era natural eren els #LPAI, Low Pathogenic Avian Influenza virus. Els #HPAI són uns artefactes molt, molt humans. #OneHealth
https://nautil.us/the-unnatural-history-of-bird-flu-1189930/
The Unnatural History of Bird Flu

H5N1 is a human creation

Nautilus

#Sequence analysis and molecular characterization of low pathogenic avian #influenza #H9N2 virus isolated from #chickens in #Sabah https://pubmed.ncbi.nlm.nih.gov/39154271/?utm_source=Feedly&utm_medium=rss&utm_campaign=None&utm_content=1LGAx__djGAJ9poBzWGqPtjEbBDtz4ipSRRPUplmgHEyyF_Ihj&fc=None&ff=20240818151352&v=2.18.0.post9+e462414

Aminoacids in #HA cleavage site displayed a characteristic #LPAI motif (PARSSR/ GLF). Notably, at position 226, isolate had aminoacid Leucine (L) demonstrating its ability to bind to receptor of #mammals, resulting in potential #risk of transmission to #humans. In addition, H9N2 isolate harboured seven potential N-glycosylation sites.

Sequence analysis and molecular characterization of low pathogenic avian influenza H9N2 virus isolated from chickens in Sabah - PubMed

Low pathogenic avian influenza (LPAI) subtype H9N2 is a causative agent that has raised increasing concern about its impact on poultry and potential public health threats. Even though H9N2 is endemic in Peninsular Malaysia, it was first reported in Sabah in August 2022, after an outbreak associated …

PubMed

Evaluating the #Impact of #LPAI #H6N1 #Outbreaks in #UK and Republic of #Ireland #Poultry #Farms during 2020, Viruses: https://www.mdpi.com/1999-4915/16/7/1147

Clinical presentation included inappetence, pronounced diarrhoea, and increased egg deformation. These signs, in combination with increased mortality, triggered a notifiable avian disease investigation

Evaluating the Impact of Low-Pathogenicity Avian Influenza H6N1 Outbreaks in United Kingdom and Republic of Ireland Poultry Farms during 2020

In January 2020, increased mortality was reported in a small broiler breeder flock in County Fermanagh, Northern Ireland. Gross pathological findings included coelomitis, oophoritis, salpingitis, visceral gout, splenomegaly, and renomegaly. Clinical presentation included inappetence, pronounced diarrhoea, and increased egg deformation. These signs, in combination with increased mortality, triggered a notifiable avian disease investigation. High pathogenicity avian influenza virus (HPAIV) was not suspected, as mortality levels and clinical signs were not consistent with HPAIV. Laboratory investigation demonstrated the causative agent to be a low-pathogenicity avian influenza virus (LPAIV), subtype H6N1, resulting in an outbreak that affected 15 premises in Northern Ireland. The H6N1 virus was also associated with infection on 13 premises in the Republic of Ireland and six in Great Britain. The close genetic relationship between the viruses in Ireland and Northern Ireland suggested a direct causal link whereas those in Great Britain were associated with exposure to a common ancestral virus. Overall, this rapidly spreading outbreak required the culling of over 2 million birds across the United Kingdom and the Republic of Ireland to stamp out the incursion. This report demonstrates the importance of investigating LPAIV outbreaks promptly, given their substantial economic impacts.

MDPI
Szablewski CM, Iwamoto C, Olsen SJ, Greene CM, Duca LM, Davis CT, Coggeshall KC, Davis WW, Emukule GO, Gould PL, Fry AM, Wentworth DE, Dugan VG, Kile JC, Azziz-Baumgartner E
Reported #Global #Avian #Influenza Detections Among #Humans and #Animals During 2013-2022: Comprehensive Review and Analysis of Available #Surveillance Data - JMIR Public Health Surveill 2023;9:e46383, doi: 10.2196/46383, PMID: 37651182 https://publichealth.jmir.org/2023/1/e46383 #research #HPAI #LPAI #panzootic
Reported Global Avian Influenza Detections Among Humans and Animals During 2013-2022: Comprehensive Review and Analysis of Available Surveillance Data

Background: Avian influenza (AI) virus detections occurred frequently in 2022 and continue to pose a health, economic, and food security risk. The most recent global analysis of official reports of animal outbreaks and human infections with all reportable AI viruses was published almost a decade ago. Increased or renewed reports of AI viruses, especially high pathogenicity H5N8 and H5N1 in birds and H5N1, H5N8, and H5N6 in humans globally, have established the need for a comprehensive review of current global AI virus surveillance data to assess the pandemic risk of AI viruses. Objective: This study aims to provide an analysis of global AI animal outbreak and human case surveillance information from the last decade by describing the circulating virus subtypes, regions and temporal trends in reporting, and country characteristics associated with AI virus outbreak reporting in animals; surveillance and reporting gaps for animals and humans are identified. Methods: We analyzed AI virus infection reports among animals and humans submitted to animal and public health authorities from January 2013 to June 2022 and compared them with reports from January 2005 to December 2012. A multivariable regression analysis was used to evaluate associations between variables of interest and reported AI virus animal outbreaks. Results: From 2013 to 2022, 52.2% (95/182) of World Organisation for Animal Health (WOAH) Member Countries identified 34 AI virus subtypes during 21,249 outbreaks. The most frequently reported subtypes were high pathogenicity AI H5N1 (10,079/21,249, 47.43%) and H5N8 (6722/21,249, 31.63%). A total of 10 high pathogenicity AI and 6 low pathogenicity AI virus subtypes were reported to the WOAH for the first time during 2013-2022. AI outbreaks in animals occurred in 26 more Member Countries than reported in the previous 8 years. Decreasing World Bank income classification was significantly associated with decreases in reported AI outbreaks (P<.001-.02). Between January 2013 and June 2022, 17/194 (8.8%) World Health Organization (WHO) Member States reported 2000 human AI virus infections of 10 virus subtypes. H7N9 (1568/2000, 78.40%) and H5N1 (254/2000, 12.70%) viruses accounted for the most human infections. As many as 8 of these 17 Member States did not report a human case prior to 2013. Of 1953 human cases with available information, 74.81% (n=1461) had a known animal exposure before onset of illness. The median time from illness onset to the notification posted on the WHO event information site was 15 days (IQR 9-30 days; mean 24 days). Seasonality patterns of animal outbreaks and human infections with AI viruses were very similar, occurred year-round, and peaked during November through May. Conclusions: Our analysis suggests that AI outbreaks are more frequently reported and geographically widespread than in the past. Global surveillance gaps include inconsistent reporting from all regions and human infection reporting delays. Continued monitoring for AI virus outbreaks in animals and human infections with AI viruses is crucial for pandemic preparedness.

JMIR Public Health and Surveillance