👏👏👏

*infections*

not *people*

*people* who keep getting *infections* are going to guarantee themselves a disability. There are only so many empty chambers in the revolver.

> Long COVID leaves telltale traces in the blood
https://www.ukri.org/news/long-covid-leaves-telltale-traces-in-the-blood/

#CovidIsNotOver #LongCovid #ReduceYourRisk #GetAsLittleCovidAsPossible #EveryRollOfTheDiceIsTenPercent

Long COVID leaves telltale traces in the blood

People with Long COVID have distinct patterns of inflammation detectable in the blood, which could potentially be targeted with immune therapies.

ht @noyes

> Results: We enrolled 90 infants. SARS-CoV-2-positive infants had poorer psychomotor development index (PDI) scores and significantly greater mildly delayed performances (MDPs) at 18–24 months (PDI p = 0.05, MDPs p = 0.03, respectively). Delta variant showed statistically significant lower MDI and PDI scores (MDI p=0.03, PDI p=0.03, respectively). A smaller head circumference of SARS-CoV-2-positive toddlers was detected in the first year (p < 0.001), which improved at the second age.

> Conclusion: SARS-CoV-2-positive neonates revealed lower PDI scores and greater MDPs at 18th-24th months. The effect is most noticeable in Delta variant. Longer-term examination of neurodevelopmental outcomes and reevaluation of these children between the ages of 5 and 12 are critical.

@novid #CovidIsNotOver #MaskUp #GetAsLittleCovidAsPossible

DIY public health is a costly endeavour -- back when every dollar of every human's discretionary spending mattered to the owner class, it might've been enough to tip the scales toward implementation of collective public health measures.

But, as much as I've spent/foregone to protect myself and my family from SARS-CoV-2 infection, it still doesn't hold a candle to what LetItRip™ is costing us, even based on dollar-value alone: https://scholar.harvard.edu/files/cutler/files/long_covid_update_7-22.pdf

@novid #CovidIsNotOver #WearARespirator #GetAsLittleCovidAsPossible

ht @inkblue01

@Brad @PacificNic it seems that thanks to some as-yet-unknown variables, some folks have a bit more in the tank that has to be drained before symptoms crop up. If they keep getting infected though, I definitely think most** of them are going to suffer a version of LC much more like typical 'longhaulers'.

The best thing anyone can do is StopGettingInfected™

#GetAsLittleCovidAsPossible

--

{**I still expect outliers, but.. 🤷}

1. Politicians need to be frank
2. Avoiding infections is still important
3. Adopt new knowledge and technology

https://medicalxpress.com/news/2023-03-viewpoint-years-pandemic-covid-wont.html

@novid

#COVID #CovidAintOver #MaskUp #N95 #GetAsLittleCovidAsPossible

Viewpoint: Three years into the pandemic, it's clear COVID won't fix itself. What we need to focus on next

On March 11 2020 the World Health Organization classified COVID as a pandemic. Three years on, it remains just that.

Medical Xpress
84% of hospital COVID patients in Sweden still had symptoms at 2 years

CIDRAP

...still no mention of #longCOVID, tho. #MaskUp #GetAsLittleCOVIDAsPossible #COVIDIsNotOver

“By normalizing #antibody titers, we found that study results converge on a consistent relationship between antibody levels and protection from #COVID-19. This finding can be useful for planning future #vaccine use, determining population #immunity, and reducing the global effects of the COVID-19 #pandemic

https://wwwnc.cdc.gov/eid/article/29/2/22-1422_article

@novid

Correlates of Protection, Thresholds of Protection, and Immunobridging among Persons with SARS-CoV-2 Infection

Correlates of Protection and SARS-CoV-2 Infection

Emerging Infectious Diseases journal