Albert Cardona"Phase-specific premotor inhibition modulates leech rhythmic motor output", Martina Radice et al. 2025
https://elifesciences.org/reviewed-preprints/104921
ElephantNo better place to get a hands-on glimpse into the various software tools @ebrains has to offer, Europe's emerging RI for brain research. Choose from over 16 tutorials for software that are already offered, like the EBRAINS Knowledge Graph for data sharing, TVB, and NEST for neural simulation, or Cobrawap for analyzing spatial activity dynamics... And myself -- I will also be there with a tutorial on #ephys data analysis and data handling with Neo. See you there! https://fosstodon.org/@ebrains@mastodon.social/113837231713079532
El Duvelle Neuro#Tetrode recordings (in a bundle): did you know that you could record the same neuron on two different tetrodes?
or even three different tetrodes??
After checking that, turns out I usually have about 5-10% of neurons that are a duplicate of another neuron, in a given 8-tetrodes recording! They are pretty easy to detect with a firing rate correlation so I can remove them from analysis.
But I bet most neuron counts in published papers are inflated of that much!
Here's an example where you can see the spike plots and waveforms of 3 different, well-isolated clusters, recorded from 3 different tetrodes!
#Hexamaze #NeuroRat #Neuroscience #Ephys #Hippocampus #PlaceCells #SpikeSorting (-related)
Redish LabI don't think it would be possible to record a single neuron on multiple tetrodes. What is the separation between your tetrodes?
#NeuroMethods #Ephys #SpikeSorting #Tetrodes
If you do need cross-correlation code, there is mex'd cross-correlation code in MClust.
#NeuroMethods #Ephys what is the fastest way to detect potential duplicate neurons after spike-sorting?
Say you’ve recorded from multiple neurons that might be detected by multiple tetrodes, you do #SpikeSorting per tetrode, and want to detect those duplicates afterwards?
I was thinking cross-correlation across all cell pairs. But my implementation is really slow. If anyone already has code for this (Matlab or Python) I’d be happy to steal it 😬
What do #Electrophysiologists who record raw data from many channels (#NeuroPixels, #Hyperdrives…) do for data backup and storage? I just bought 2 x 4Tb external drives and it looks like they won’t be enough (at all). Is there a cheap and reliable AND huge storage way to do this?
What’s your best guide on extracellular recordings #waveform shapes to know if you’re recording from soma, axon, dendrite etc.? (Most interested about #Hippocampus of course)
#Ephys #Electrophysiology #NeuroMethods
#Ephys #Electrophysiology #NeuroMethods
spikeinterface📢📢📢
#ephys and #spikesorting community!
We are thrilled to announce the "Tools and Methods for Next Generation Electrophysiology" event, happening in Edinburgh from May 27-31.
Registration link:
https://forms.gle/6dEdeR7sD7u6u8rU8
More info on the event webpage:
https://spikeinterface.github.io/spikeinterface-events/spikeinterface-workshop-2024/
Tools and Methods for Next Generation Electrophysiology
Informatics Forum, University of Edinburgh Workshop 27-28th May 2024 Hackathon 29-31st May 2024 Please contact Matthias Hennig ([email protected]) if you need an invitation letter for visa purposes.
Moritz NegwerReally cool #lightsheet #microscopy application:
An atlas of the developing mouse brain (DevATLAS from Yongsoo Kim's lab), combined with a new neuronal activity reporter line (Npas4-Cre), shows the order in which brain regions become active in the first postnatal weeks.
(And they have #ephys and #rnaseq too!)
Spatiotemporal Mapping and Molecular Basis of Whole-brain Circuit Maturation
Xue et al., preprint on biorxiv, 2024
https://doi.org/10.1101/2024.01.03.572456
