"Phase-specific premotor inhibition modulates leech rhythmic motor output", Martina Radice et al. 2025
https://elifesciences.org/reviewed-preprints/104921

#neuroscience #leech #ephys #motoneurons

Phase-specific premotor inhibition modulates leech rhythmic motor output

( #Perth, #WA, #Australia)

From Christopher Latella

If you, or someone you know in the #Perth community suffers from Myalgic Encephalomyelitis/Chronic Fatigue Syndrome please get in touch.

@mecfs

#MyalgicEncephalomyelitis #ChronicFatigueSyndrome #MEcfs #CFS #PwME #MyalgicE #CFSME #MEeps #motoneurons

Regulating firing rate. Populations of respiratory #motoneurons use combinations of 2 activity regulators (Na+ pumps & Kv7 channels) that monitor different readouts of firing rate to maintain #neuronal output @PellizzariSarah @santin_joe &co #PLOSBiology https://plos.io/3Db8oX4
Neuron populations use variable combinations of short-term feedback mechanisms to stabilize firing rate

Neurons tightly regulate firing rate, and a failure to do so leads to multiple neurological disorders; how is this done? This study of respiratory motoneurons shows that populations of neurons use unique combinations of two activity regulators (Na+ pumps and Kv7 channels) that monitor different readouts of firing rate to maintain neuronal output.

Regulating firing rate. Populations of respiratory #motoneurons use combinations of 2 activity regulators (Na+ pumps & Kv7 channels) that monitor different readouts of firing rate to maintain #neuronal output @PellizzariSarah @santin_joe &co #PLOSBiology https://plos.io/3Db8oX4
Neuron populations use variable combinations of short-term feedback mechanisms to stabilize firing rate

Neurons tightly regulate firing rate, and a failure to do so leads to multiple neurological disorders; how is this done? This study of respiratory motoneurons shows that populations of neurons use unique combinations of two activity regulators (Na+ pumps and Kv7 channels) that monitor different readouts of firing rate to maintain neuronal output.

Regulating firing rate. Populations of respiratory #motoneurons use combinations of 2 activity regulators (Na+ pumps & Kv7 channels) that monitor different readouts of firing rate to maintain #neuronal output @PellizzariSarah @santin_joe &co #PLOSBiology https://plos.io/3Db8oX4
Neuron populations use variable combinations of short-term feedback mechanisms to stabilize firing rate

Neurons tightly regulate firing rate, and a failure to do so leads to multiple neurological disorders; how is this done? This study of respiratory motoneurons shows that populations of neurons use unique combinations of two activity regulators (Na+ pumps and Kv7 channels) that monitor different readouts of firing rate to maintain neuronal output.