Clinical trial: A Clinical Study Evaluating the Safety and Preliminary Efficacy of Universal Allogeneic CAR T-cell Therapy Targeting CD19 and BCMA(QT-019C) in Patients With Relapsed / Refractory Neurological Autoimmune Diseases
Clinical trial: A Clinical Study Evaluating the Safety and Preliminary Efficacy of Universal Allogeneic CAR T-cell Therapy Targeting CD19 and BCMA(QT-019C) in Patients With Relapsed / Refractory Neurological Autoimmune Diseases
Clinical trial: Randomized, Single-blind, Placebo-controlled Clinical Trial to Evaluate the
Safety and Efficacy of Melatonin Administration in Patients With Multiple
Progressive Primary Sclerosis (MELATOMS)
Clinical trial: Bringing the Outdoors In: Virtual Nature Walks for Depression in Multiple Sclerosis (MS) Patients
Clinical trial: Investigating Specific Gait Patterns in Individuals Living With Multiple Sclerosis
Clinical trial: A Phase 1, Open-label, Multiple Ascending Dose Basket Study to Evaluate the Safety and Activity of DR-0201 in Patients With Select Autoimmune Rheumatic Diseases
Clinical trial: A Pilot Study of Ublituximab in People With MS Experiencing Wearing Off Phenomena While Receiving Treatment With Ocrelizumab
Clinical trial: Effect of Sensory Integration Therapy on Gait Variability and Quality Of Life in Patients With Multiple Sclerosis: A Randomized Controlled Trial
Neurotmesis remains a significant clinical challenge due to limited intrinsic regenerative capacity and suboptimal outcomes of current therapies. Mesenchymal stromal cells (MSCs) secretome has emerged as a promising cell-free alternative. This study aimed to evaluate the regenerative efficacy of primed MSC secretome in a rat model of sciatic nerve neurotmesis. Secretome priming enhanced the sec...
The retinoid X receptor agonist bexarotene promotes remyelination in patients with multiple sclerosis. Murine studies have also shown that RXR agonists have anti-inflammatory effects.
Clinical trial: Exploring Cognitive Recovery: the Impact of Sensor-based Robotic Rehabilitation in Neurological and Neurodegenerative Disorders