Clinical trial: Comparison of Gait Metrics in Patients With Stroke, Traumatic Brain Injury, and Multiple Sclerosis Before and After Functional Electrical Stimulation

https://clinicaltrials.gov/study/NCT07492602?utm_source=fediverse&utm_medium=mastodon&utm_content=trial_20305

#ClinicalTrials #MultipleSclerosis #MSchat #Neurology

Clinical trial: Comparison of the Performance of the 2024 and 2017 McDonald Criteria for the Diagnosis of Multiple Sclerosis in Real Life

https://clinicaltrials.gov/study/NCT07492667?utm_source=fediverse&utm_medium=mastodon&utm_content=trial_20306

#ClinicalTrials #MultipleSclerosis #MSchat #Neurology

Clinical trial: Context- and Terrain-aware Gait Analysis and Visualisation

https://clinicaltrials.gov/study/NCT07491588?utm_source=fediverse&utm_medium=mastodon&utm_content=trial_20293

#ClinicalTrials #MultipleSclerosis #MSchat #Neurology

Clinical trial: FACTORS ASSOCIATED WITH URINARY INCONTINENCE AND EVALUATION OF PELVIC FLOOR MUSCLE ACTIVITY IN PATIENTS WITH MULTIPLE SCLEROSIS: CROSS-SECTIONAL STUDY

https://clinicaltrials.gov/study/NCT07489794?utm_source=fediverse&utm_medium=mastodon&utm_content=trial_20294

#ClinicalTrials #MultipleSclerosis #MSchat #Neurology

https://gregory-ms.com/articles/313913/?utm_source=fediverse&utm_medium=mastodon&utm_content=article_313913

Polylamin-1 pre-polymerized in acidic acetate buffer at pH 4 induced spontaneous formation of MBP-positive myelin sheaths and enhanced alignment of Schwann cells with neurite bundles. Laminin at pH 7 preferentially supported neurite outgrowth and Schwann cell migration. Poly-l-lysine showed limited organization and responsiveness.

#MultipleSclerosis #MSchat #MS #Neurology

Clinical trial: Comparison of the Effects of Pelvic Floor Strengthening and Relaxation Exercises Delivered Via Telerehabilitation in Women Diagnosed With Multiple Sclerosis: A Randomized Controlled Study

https://clinicaltrials.gov/study/NCT07485556?utm_source=fediverse&utm_medium=mastodon&utm_content=trial_20275

#ClinicalTrials #MultipleSclerosis #MSchat #Neurology

Clinical trial: Motor Asymmetry in Progressive Multiple Sclerosis Patients

https://clinicaltrials.gov/study/NCT04918225?utm_source=fediverse&utm_medium=mastodon&utm_content=trial_20261

#ClinicalTrials #MultipleSclerosis #MSchat #Neurology

Clinical trial: A Multicenter, Open-label, Single-arm Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Ocrelizumab in Chinese Patients With Relapsing Multiple Sclerosis and Primary Progressive Multiple Sclerosis

https://clinicaltrials.gov/study/NCT07483450?utm_source=fediverse&utm_medium=mastodon&utm_content=trial_20262

#ClinicalTrials #MultipleSclerosis #MSchat #Neurology

Clinical trial: A Phase 3 Study With an Open-Label Extension in Pediatric Participants to Evaluate the Safety, Efficacy, and Pharmacokinetics of Diroximel Fumarate and Dimethyl Fumarate for the Treatment of Relapsing Forms of Multiple Sclerosis

https://clinicaltrials.gov/study/NCT07483632?utm_source=fediverse&utm_medium=mastodon&utm_content=trial_20263

#ClinicalTrials #MultipleSclerosis #MSchat #Neurology

https://gregory-ms.com/articles/313776/?utm_source=fediverse&utm_medium=mastodon&utm_content=article_313776

Multiple sclerosis (MS) is an autoimmune neurodegenerative disorder of the central nervous system. Targeting embryonic ectoderm development (EED) is a potential therapeutic strategy for treating MS. Trisubstituted pyridine derivatives are EED-H3K27me3 inhibitors for MS treatment. Compounds 19 and 21 demonstrate potent EED binding affinity

#MultipleSclerosis #MSchat #MS #Neurology