
Yo, even though people often say “cannabinoids are anti-inflammatory”, the truth is that THC probably isn’t a powerful anti-inflammatory drug. CBD, on the other hand actually has some evidence suggesting it might be quite anti-inflammatory (but don’t come at me asking for the mechanisms, because as I mentioned in earlier posts we still don’t really know)! The image below shows a few of the proposed anti-inflammatory pathways for CBD -- including TRPV1 activation, NADPH oxidase modulation, and the NRF2 axis. If you're like me and thinking "wtf is that" i do a quick description below - TRPV1 (aka the “hot chili pepper” receptor) detects heat and chemical irritants. When activated by CBD, it may reduce the release of pro-inflammatory neuropeptides and shift pain signaling. NADPH oxidase is an enzyme complex that produces reactive oxygen species (i.e ROS). CBD appears to dampen this enzyme’s activity, limiting oxidative stress, which is a key driver of inflammation. NRF2 is a transcription factor that turns on the body’s antioxidant defense genes. CBD may enhance this pathway, neutralizing ROS and restoring the redox balance during inflammation. SOURCE: Urlić H, Kumrić M, Pavlović N, Dujić G, Dujić Ž, Božić J. Cardiovascular Effects of Cannabidiol: From Molecular Mechanisms to Clinical Implementation. Int J Mol Sci. 2025;26(19):9610. Published 2025 Oct 1. doi:10.3390/ijms26199610

🦠 🎉 🤦🏻♂️ 🇺🇸 More than 150 unvaccinated students in South Carolina are sitting at home right now because of a measles outbreak. Public schools in Spartanburg County sent them home to quarantine after exposure. Measles. The disease we supposedly eradicated before Friends went off the air. The Department of Health confirmed at least 11 cases statewide this year, eight since September. That’s a Van Halen comeback tour. Measles spreads through the air and hangs around long enough to infect someone who walks in two hours later. It can damage lungs, hearing, and cognition. It can kill. But sure, let’s keep pretending “personal choice” is sacred when it ends up in the ICU, just like asking people at the resort to only swim in the area of the pool where the diarrhea isn't. Parents who skip vaccines call it freedom. I call it gambling with borrowed chips. Schools become collateral. The community pays the price. Kids too young to vaccinate or too sick to respond get caught in the fallout. The state has quarantine laws for a reason. It’s not tyranny. It’s math. When vaccination rates drop below 95 percent, herd immunity collapses. South Carolina sits closer to 92.7. Fun on a bun. The story isn’t about fear of needles. It’s about the collapse of trust. Decades of disinformation turned science into a belief system. Parents started treating experts like politicians. Public health departments got gutted. The CDC lost credibility. TikTok and RFK filled the vacuum. Now local officials beg for compliance while conspiracy peddlers get paid in clicks. We keep treating measles like a history lesson. It’s a warning. And we’re ignoring it again. If this hits home, toss it a like, a repost, comment, or tag someone you may be ambivalent about. One click makes a bigger difference than you think. Are you new here? First off, my condolences. But welcome. Glad you found me. Stick around, hit follow, and help me get to 50,000 follower goal by year’s end. The more of us here, the harder we are to ignore. SOURCE IN COMMENTS ⬇️ | 22 comments on LinkedIn