Ali TwelvetreesDec 21, 2024
Our preprint is up! Take a look if you like kinesin, microtubule transport, single molecule FRET or biophysics. It’s a bit of shift to how we’ve been used to thinking about kinesin-1 regulation as we try to get a handle on its conformational dynamics. Super proud of to have this milestone out in the world and all the hard work it represents from everyone involved.
#kinesin #microtubules #biophys #smFRET #SingleMolecule #AxonalTransport https://biologists.social/@TwelvetreesLab/113691748206473977
Twelvetrees Lab (@[email protected])

Kinesin-1 is highly flexible and adopts an open conformation in the absence of cargo http://biorxiv.org/cgi/content/short/2024.12.20.629623v1?rss=1

biologists.social
Ali TwelvetreesJul 8, 2023

Hello! A new intro for a new instance.

I lead a research group trying to figure out axonal transport and neurodegeneration. A big emphasis on the microtubules and their motors, but really the transport of anything that doesn't have a membrane around it. For this we use a lot of single molecule methods and live cell imaging. I also post about research culture.

#introduction #kinesin #dynein #microtubules #neurodegeneration #AxonalTransport #neurobiology #SingleMolecule #CellBiology

Ali TwelvetreesNov 2, 2022

Hello #ScienceMastodon!

I am a molecular and cellular neurobiologist leading a research group trying to figure out #AxonalTransport & #neurodegeneration. A big emphasis on #microtubules, #kinesin and #dynein, but really the transport of anything that doesn't have a membrane around it. We use a lot of #SingleMolecule methods and #LiveCellImaging.

I also post about #researchculture, particularly how we can better invest in people so they can do great science.

#introduction