RhyothemisPros and Cons of APOE4 Homozygosity and Effects on Neuroplasticity, Malnutrition, and Infections in Early Life Adversity, Alzheimer’s Disease, and Alzheimer’s Prevention [2024]
https://doi.org/10.3233/JAD-240888
Intake of psyllium seed husk reduces white matter damage in a rat model of chronic cerebral hypoperfusion [2019]
https://pubmed.ncbi.nlm.nih.gov/31103857/
#CerebralHypoperfusion #Brain #perfusion #hypoperfusion #psyllium #arabinoxylan #NaturalProducts #FunctionalFoods
#2BadItsPaywalled
Intake of psyllium seed husk reduces white matter damage in a rat model of chronic cerebral hypoperfusion - PubMed
Vascular dementia (VaD) develops through a pre-VaD step during which blood vessels narrow due to atherosclerosis attributed to risk factors, including hyperlipidemia. This is followed by a VaD progression step during which inadequate blood supply results in white matter damage and consequent cogniti …
Interesting article -
#2badItsPaywalled
(and also, it isn't about climate change)
Here's an open access academic article about toxic airplane cabin air -
Burden of Proof: The Debate Surrounding Aerotoxic Syndrome [2022]
https://pmc.ncbi.nlm.nih.gov/articles/PMC9452852/
"... some manufacturers developed a safer alternative. Boeing Aircraft introduced a new air intake system for the Boeing 787 Dreamliner, which does not use bleed air to supply the cabin; instead, air intakes have been mounted along the root of the front wings, thereby reducing the risk of contamination."
#AerotoxicSyndrome #AirTravel #OccupationalHealth #organophosphates #AirPollution
Burden of Proof: The Debate Surrounding Aerotoxic Syndrome
Since the 1980s, some commercial airline pilots and flight crews in the United States, United Kingdom and Australia began to report an illness they believed was caused by exposure to contaminated cabin air. Despite a body of scientific research and ...
“To test their findings, the researchers isolated a protein associated with aging in the aortas of mice, and injected it into young mice to observe the results. ..."
The senoprotein tested was Gas6; it is a vitamin K dependent protein and it's activities are dependent on carboxylation. Unfortunately the original research article * is paywalled, so no details on carboxylation ...
* Comprehensive human proteome profiles across a 50-year lifespan reveal aging trajectories and signatures [2025]
https://doi.org/10.1016/j.cell.2025.06.047
Effect of vitamin A supplementation on iron status in humans: A systematic review and meta-analysis [2018]
https://pubmed.ncbi.nlm.nih.gov/29336593/
"Therefore, vitamin A supplementation alone may reduce the risk of anemia, by improving hemoglobin and ferritin levels in individuals with low serum retinol levels."
#2badItsPaywalled #IronDeficiency #anemia #ferritin #VitaminA
Effect of vitamin A supplementation on iron status in humans: A systematic review and meta-analysis - PubMed
Anemia is a worldwide public health problem that can be related to many causes, including vitamin A deficiency. The aim of this study was to assess and estimate the effect of vitamin A supplementation (VAS) on iron status biomarkers and anemia in humans. Six databases, including Cochrane, EMBASE, LI …
Interesting case report:
Early coma in intussusception: Endogenous opioid induced?
https://pubmed.ncbi.nlm.nih.gov/3562307/
Abstract
A decreased level of consciousness with little abdominal pain or gastrointestinal symptoms is an uncommon, but well described, presentation of infantile intussusception. Its etiology is unclear. We describe a 10-month-old male who presented with coma and miosis, reversible with bolus injections of naloxone on three separate occasions. No opiates were involved and an intussusception was subsequently found. We speculate that the coma and miosis were induced by an endogenous opioid which could also mask the abdominal pain, thus explaining this presentation of intussusception. If so, miosis would be a valuable clue for diagnosing such children.
Early coma in intussusception: endogenous opioid induced? - PubMed
A decreased level of consciousness with little abdominal pain or gastrointestinal symptoms is an uncommon, but well described, presentation of infantile intussusception. Its etiology is unclear. We describe a 10-month-old male who presented with coma and miosis, reversible with bolus injections of n …
"Moreover, genipin cross-linked the extracellular matrix (ECM), increased the stiffness of the ECM, reorganized the actin cytoskeleton, and promoted transcription of yes-associated protein–dependent genes."
https://www.science.org/doi/10.1126/scitranslmed.adq2418
#2badItsPaywalled #genipin #NaturalProducts #ExtracellularMatrix
Antianxiety and Antidepressant Activity Guided Isolation and Characterization of Gossypetin from Hibiscus sabdariffa Linn. Calyces
https://doi.org/10.1080/22311866.2019.1615552
I can feel a difference when I drink hibiscus tea. It tastes good, but it's really acidic and I worry about my teeth.
Marital Status and Mortality: The National Longitudinal Mortality Study
https://doi.org/10.1016/S1047-2797(99)00052-6
really annoyed that this study is paywalled since it is a product of the Census Bureau
my taxpayer money is lining the pockets of Elsevier, as usual
First sentence in this paywalled article: "Pascal Geldsetzer believes in open access, in disseminating science as quickly as it happens."
I understand good articles cost money to produce, but - it just seems a bit ironic. And I can't help but be disappointed that I can't access this article since it sounds interesting.