Vaclav Hanzl

@[email protected]
30 Followers
85 Following
75 Posts
Spent most of my professional life in Speech Recognition. Occasionally, I do various divertimento projects outside AI, like typesetting a Japanese textbook or software for a scary hydraulic machine or web about my wife's books.
GitHubhttps://github.com/vaclavhanzl
LinkedInhttps://www.linkedin.com/in/vaclav-hanzl-326140199/
Printableshttps://www.printables.com/@vaclavh_797838
Vaclav HanzlDec 14
No panic, just being ready:
- downloaded all emails and Google cloud files at takeout.google.com - went much smoother than expected
- my email signature now says what my local backup email is "should transatlantic cables ever burn"
- forwarding at least Primary inbox messages to that backup
Vaclav HanzlJun 28, 2025
My Evil Cube print files are public now... The solution is not. Please let me know if you find one. #FreeCAD https://www.printables.com/model/1339793-evil-cube
Vaclav HanzlJun 7, 2025
HackerNewsJun 6, 2025
The time bomb in the tax code that's fueling mass tech layoffs
Link: https://qz.com/tech-layoffs-tax-code-trump-section-174-microsoft-meta-1851783502
Comments: https://news.ycombinator.com/item?id=44180533
The hidden time bomb in the tax code that's fueling mass tech layoffs

A decades-old tax rule helped build America's tech economy. A quiet change under Trump helped dismantle it

Quartz
Vaclav HanzlNov 6, 2024
bert hubert 🇺🇦🇪🇺🇺🇦Nov 6, 2024
If as it appears likely that 🇪🇺will have to start defending itself against Russia 🇷🇺 alone it may be good to realize our IT systems and society aren’t remotely ready for that. https://berthub.eu/articles/posts/cyber-security-pre-war-reality-check/
Cyber Security: A Pre-War Reality Check - Bert Hubert's writings

This is a lightly edited transcript of my presentation today at the ACCSS/NCSC/Surf seminar ‘Cyber Security and Society’. I want to thank the organizers for inviting me to their conference & giving me a great opportunity to talk about something I worry about a lot. Here are the original slides with notes, which may be useful to view together with the text below. In the notes there are also additional URLs that back up the claims I make in what follows.

Bert Hubert's writings
Vaclav HanzlAug 25, 2024
Tiger #mosquito finds targets using #infrared vision. Now do your research and Nature article (if you are in this field), thank me later for the tip! :) Well, this was my idea, I was surprised how directly these beasts attacked me in Nice. I shut down my Mac - and, surprise, it went after the Mac, not me! But it is too late, now I see an article about Aedes aegypti using infrared, came out just few days ago! So, maybe I smashed Ae. aegypti, not Ae. albopictus. Hard to tell, I used force...
Vaclav HanzlApr 7, 2024
I have never read Don Winslow's book but I like him anyway. And his decision to do other things than writing books this year. He does something important for me. And you. https://www.rollingstone.com/culture/culture-features/don-winslow-last-novel-political-activism-trump-1234997655/
Don Winslow’s Crusade Against Trump: ‘Do You Want a Narcissistic Sociopath in the White House?’

Don Winslow, author of City in Ruins, says he has published his last novel and is devoting his energy to political activism and taking on Trump

Rolling Stone
Vaclav HanzlFeb 6, 2024
Steve HermanFeb 6, 2024
US Court of Appeals rules Donald Trump doesn't have presidential immunity and can be prosecuted on charges of plotting to overturn the 2020 election. https://www.documentcloud.org/documents/24409122-immunityopn020624
DocumentCloud

Vaclav HanzlDec 11, 2023
Airplanes have black boxes, computers have log files - both invaluable to find out what happened. Can we do it inside a living cell? Yes! I just found out that people work on this. See e.g. Recording of cellular physiological histories, https://www.nature.com/articles/s41587-022-01586-7
#proteins #biochemistry #forensics
Recording of cellular physiological histories along optically readable self-assembling protein chains - Nature Biotechnology

A history of cellular events is recorded in self-assembling protein chains.

Nature
Vaclav HanzlApr 21, 2023

Reading #AlphaFold2 and #OMSF #OpenFold code is great but with #protein #molecules in your hands you feel it better. Designing the kit in #FreeCAD ensures you know bond lengths and angles etc. So I spent few days learning and printing. The kit is optimized for protein #folding, single bond rotates but can be fixed in #peptide bond, it keeps shape even before adding #hydrogen #bonds in #alphahelix (or pair #RNA bases by H-bond).

Print your #kit and enjoy #biochemistry!

https://www.printables.com/model/457984-molecules-for-protein-folding

Printables

Vaclav HanzlMar 31, 2023
Lucas NivonMar 30, 2023
With protein AI advancing, how can it help us design new biologics from natural proteins? We've summarized our in silico experiments led by Steven Lewis at Cyrus #ai #biotech #drugdiscovery https://cyrusbio.com/2023/03/the-impact-of-new-protein-ai-tools-on-real-world-biologics-discovery/
The impact of new protein AI tools on real-world biologics discovery: Protein AI tools are useful for aggressive protein design, while physics based tools continue to be required for re-design of natural proteins for most cases

By Steven Lewis, Dan Farrell, Brandon Frenz, Ragul Gowthaman, Ryan Pavlovicz, David Thieker, Indigo King, Sam DeLuca, Yifan Song, and Lucas Nivon As new tools come online daily applying deep learning architectures to new problems, the field of artificial intelligence is replete with claims, from the fairly pedestrian to aggressive claims of having “solved” entire […]

Cyrus Biotech | Molecular Modeling and Design