The #peptide problem: Hype is outrunning the evidence of efficacy.
Health #Canada issues warning about online sales and lack of research on humans.
“Until then, buying vials of dry powder, reconstituting it in sterile water, and injecting the cocktail with online-purchased needles will not provide proof of anything.
It is high-risk, uncontrolled human self-experimentation.”
https://theconversation.com/the-peptide-problem-hype-is-outrunning-the-evidence-280715
Palladium ist ein unverzichtbares Edelmetall für die Medizin. Doch seine Rückgewinnung aus Industrieabfällen ist bisher aufwendig und umweltbelastend. Die Forschungsgruppe Pep2Rec am Helmholtz-Zentrum Dresden-Rossendorf setzt daher auf winzige Eiweißketten, die das Metall wie eine biologische Angel aus Lösungen fischen.
#Palladium #Peptide #WissenschaftPodcast #Forschungsquartett
Das Edelmetall Palladium aus Industrieabfällen zu recyceln, ist aufwendig. Die Forschungsgruppe Pep2Rec hat eine Lösung entwickelt.
Another satisfied client Vicky 🥳🎉🎊
12 weeks transformation, Consistency is key 💪 Never give up!!
Send me a massage to join me on the ozempic fitness program.
#peptide
New paper out: Meet Psysol 3—a novel #cyclotide #NaturalProduct from Psychotria solitudinum. A #cystine_knot #peptide that potently inhibits prolyl oligopeptidase, expanding chemical space for POP #pharmacology and #DrugDiscovery. #ChemicalBiology @univienna #PeptAIDes #ZK81B @fwf
Peptides from natural sources have often served as valuable leads in drug discovery. Plant-derived protease inhibitors are a notable class, yet their distribution, diversity, and targets remain underexplored. Here, eleven tropical Psychotria species were screened for cyclic cysteine-rich peptides, with extracts showing concentration-dependent inhibition of human prolyl oligopeptidase (POP). Peptidomics combining mass spectrometry and transcriptome mining revealed multiple inhibitory peptides. From Psychotria solitudinum, which contained 37 peptides, a novel peptide (psysol 3) was purified and sequenced. Its synthetic analogue inhibited POP with an IC50 of ~ 1.3 µM. Sequence analysis and synthetic probes identified loop 3 as the inhibitory motif. Psysol 3 is a new probe for POP pharmacology and future structure–activity studies.
Stanford researchers identify peptide that may suppress appetite with fewer side effects than Ozempic
📰 Original title: Stanford scientists discover “natural Ozempic” without side effects
🤖 IA: It's clickbait ⚠️
👥 Usuarios: It's clickbait ⚠️
View full AI summary: https://killbait.com/en/stanford-researchers-identify-peptide-that-may-suppress-appetite-with-fewer-side-effects-than-ozempic/?redirpost=81b8211e-6a97-47c7-ba59-707b4f139927
Researchers at Stanford Medicine have identified a naturally occurring peptide that could potentially replicate some of the appetite-suppressing and weight-loss effects of semaglutide (marketed as…
Stanford researchers identify peptide that may suppress appetite with fewer side effects than Ozempic
📰 Original title: Stanford scientists discover “natural Ozempic” without side effects
🤖 IA: It's clickbait ⚠️
👥 Usuarios: It's clickbait ⚠️
View full AI summary: https://killbait.com/en/stanford-researchers-identify-peptide-that-may-suppress-appetite-with-fewer-side-effects-than-ozempic/?redirpost=81b8211e-6a97-47c7-ba59-707b4f139927
Researchers at Stanford Medicine have identified a naturally occurring peptide that could potentially replicate some of the appetite-suppressing and weight-loss effects of semaglutide (marketed as…
Single-molecule #peptide #sequencing through reverse translation of peptides into DNA
https://www.nature.com/articles/s41587-026-03061-z
everything that can be bound with/converted to DNA can be "sequenced": it's sort of like SBS, but here DNA oligos are used instead of individual DNA bases and later actual SBS is performed to decode each oligo sequence... every read will inform about single aa at single position from single protein.
to sequence a protein with 300 aa, you'll need to sequence at least 300 reads!
neat!
Wie können digitale Tools die mentale Gesundheit unterstützen? Und welches Potenzial bergen Peptide für die Antibiotikaforschung? Die Max-Planck-Gesellschaft bietet Antworten.
#Actiself #Antibiotika #MaxPlanckInstitutFürPsychiatrie #MaxPlanckInstitutFürBildungsforschung #MaxPlanckInstitutFürTerrestrischeMikrobiologie #MentaleGesundheit #Peptide #Forschungsquartett
Wie können digitale Tools die mentale Gesundheit unterstützen? Und welches Potenzial bergen Peptide für die Antibiotikaforschung?
Nevada Regulators Fine Peptide Providers at Anti-Aging Festival Where Two Women Became Critically Ill
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Three individuals, along with the group accused of supplying the peptides, were fined between $5,000 and $10,000 for their involvement in an incident at the Revolution Against Aging and Death Festival in Las Vegas last summer.
https://www.propublica.org/article/raadfest-peptide-injections-nevada-fines?utm_source=mastodon&utm_medium=social&utm_campaign=mastodon-post
Three individuals, along with the group accused of supplying the peptides, were fined between $5,000 and $10,000 for their involvement in an incident at the Revolution Against Aging and Death Festival in Las Vegas last summer.
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