Tyson Shepherd

@trshepherd
30 Followers
123 Following
123 Posts
Synthetic biologist, microbial engineer, data wrangler, Senior Director at Alta Resource Technologies
#synbio
#syntheticbiology

#Newswire: Melt&Marble, the Swedish biotech company specializing in microbial fermentation-derived fats, has achieved self-affirmed GRAS (Generally Recognised as Safe) status for its MeltyMarble fat ingredient, clearing a path for commercialization in the United States.

#microbial #fat #fermentation #meat #dairy #ingredients #biotech #foodtech #regulatory #marketaccess #confectionery #innovation #sustainability #startups #sweden #pressrelease

https://www.proteinreport.org/newswire/meltmarble-achieves-self-gras-paving-the-way-for-us-sales

Sweden's Melt&Marble Secures GRAS Status for Fermented Fat, Opening US Market

Swedish biotech Melt&Marble secures GRAS status for its microbial fermentation-derived fat MeltyMarble, enabling US market entry for food applications.

Once you realize it’s not “age verification”, but actually “identity verification”, then it’s easy to understand that the real goal is “papers, please” for the entire internet.
You are here.
We've breached 430 ppm CO2.
#climatechange

If you're passionate about engineering protein active sites and love using the latest tools in high-throughput #protein #discovery have a look at Alta's open positions. My group is expanding our protein #engineering group to build on our unique approach to precision separations of critical minerals.

https://altatech.io/careers/

Careers

Alta Resource Technologies Inc.

If you love microbial production and are passionate about engineering the perfect expression host using high-throughput approaches, have a look at Alta's open positions - my team is hiring a strain engineer:

https://altatech.io/careers/

#microbes #bacillus #protein #REE

Careers

Alta Resource Technologies Inc.

Our first Fediverse app dates back to 2017, when Fedilab was called Mastalab. Since then, we've contributed with different apps in the free software world.

With Holos, we're stepping off our beaten path, offering a new concept: having your ActivityPub server running on your phone without changing how you use it. Beyond everything belonging to you (database on your phone and keys for signing), the app doesn't let it show, it acts like any other. (1/2)

Hot off the press! Our paper, “Global comparative structural analysis of responses to protein phosphorylation”, is now out in Nature Communications!

Protein phosphorylation is a key regulator of cellular processes: it’s everywhere, but the function and relevance of most phosphosites remain unknown. Understanding what these sites actually do means uncovering the structural mechanisms through which phosphorylation acts, and surprisingly, those have been much less explored than you might think. So we asked: across the entire Protein Data Bank, how does phosphorylation affect protein structure?

Here are some of the main takeaways:

https://www.nature.com/articles/s41467-025-64116-4

#bioinformatics #StructuralBiology @bioinformatics @structbio

Global comparative structural analysis of responses to protein phosphorylation - Nature Communications

Phosphorylation is central to protein regulation, yet its structural mechanisms remain poorly understood. Here, the authors conduct a global, systematic analysis of phosphorylated versus non-phosphorylated structures, revealing general trends of structural regulation.

Nature
Hey if you’re coming here from #BlueSky please be welcome! We’re happy you’re here. It’s not that intense, I promise. Most of us are chill. Pull up a seat and tell us about yourselves. ✨
Are people really being hired through Mastodon posts? I feel embarrassed to put my CV on here but I see a lot of people doing it and my workplaces and funds are illegally removing the only women and would appreciate any help finding remote work in STEM
https://ssh25.tiiny.site/
#fedihire #getfedihired
Public_CV_SSH_25-docx

Public_CV_SSH_25-docx

"A growing number of scientists believe that the SARS-CoV-2 virus may instead be subtly altering our immune systems. If correct, their hypothesis will change how we understand everything from respiratory syncytial virus (RSV) to shingles to sepsis."

God damn, finally.

https://www.bmj.com/content/390/bmj.r1733

#PublicHealth #SARSCoV2 #CovidIsNotOver

Why scientists are rethinking the immune effects of SARS-CoV-2

“Immunity debt,” a theory to explain the global surge in non-covid infections since pandemic restrictions were lifted, is increasingly being challenged by emerging evidence. Nick Tsergas reports Mycoplasma pneumoniae is a bacterial infection not known to cause widespread hospital admissions. “I can count on my two hands the number of times I’d ever seen mycoplasma pneumoniae before 2023,” says Samira Jeimy, clinical immunologist at the University of Western Ontario. “All of a sudden I feel like everybody has it.”1 Over the past three years similar reports have circulated of rising bacterial infections, flare-ups of old viruses becoming more common, and children landing in hospital with diseases not usually seen in young, healthy people. One explanation offered by public health leaders has been “immunity debt”2—the idea that precautions taken in the covid pandemic suppressed routine exposures to circulating pathogens, leaving people more vulnerable to them when restrictions were lifted. The theory landed in the public consciousness at the right moment. A simple idea that sounded like science, it soothed a public seeking answers just as the world was returning to a semblance of normality. And it served a policy function, allowing governments to focus on economic recovery. But its explanatory power has faded as the number of non-covid infections has kept rising each year. A 2024 analysis by the US Centers for Disease Control and Prevention3 found that invasive group A strep infections saw their most dramatic year-on-year increase from 2021 to 2022, well after most precautions had been lifted in the US. Rates have been abnormally high since then, raising questions about what might be behind the trend. A growing number of scientists believe that the SARS-CoV-2 virus may instead be subtly altering our immune systems. If correct, their hypothesis will change how we understand everything …

The BMJ