PopgenTUM

@[email protected]
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Population Genetics group lead by Prof. Aurélien Tellier @TU_Muenchen. We are combining theoretical and empirical work to study genome evolution in natural populations.
Theoretical methodsStochastics in Evolution; Bayesian inference methods, SMC, DL;
OmicsGenomes, Transcriptomes, Methylomes, Conservation genomics;
PlantsGrowth and yield, Plant parasite interactions, Seed germination;
Lab websitehttps://www.popgen.wzw.tum.de/home/
PopgenTUMJan 23, 2023
https://biorxiv.org/cgi/content/short/2023.01.18.524537v1
We show a positive correlation between the age of selective sweeps at genes in these network and their degree of connectivity. Should we interpret these findings as older sweeps occurring at more connected genes in a network during the adaptation to drought stress?
#adaptationgenomics #SelectiveSweep #GeneNetworks #Solanum
PopgenTUMJan 23, 2023
A new preprint with Dr Wei, Dr Sharifova, and @gustavo_silva is avalable: Evolution of two gene networks underlying adaptation to drought stress in the wild tomato Solanum chilense.
https://biorxiv.org/cgi/content/short/2023.01.18.524537v1
We study the evolutionary processes driving the evolution of two gene networks underlying response to drought.
PopgenTUMDec 20, 2022
A #Postdoc position is available in our lab at @tu_muenchen on fungal #popgen in Blumeria species and #transposableelements. Knowledge and practical experience in bioinformatics and population genetics analysis of full genome data is desired. The salary is according to German/Bavarian income level TV-L E13 (100%). Informal inquiries can be addressed to me via email ([email protected]). Please RT. #EvolutionaryBiology #Genomics #Bioinformatics #Proteomics @jobsecoevo
Show threadPopgenTUMDec 20, 2022
We also found that the fixation of adaptive alleles in genes related to different biological functions occurs concomitantly, probably in response to strong climatic changes.
PopgenTUMDec 20, 2022
Our paper, with Dr Wei and @gustavo_silva about genomics of colonization stressful habitats around the Atacama in a wild tomato species is out in @NewPhytologist. Interestingly, our results support that colonization to new stressful habitats is mediated by the emergence of adaptive variation in numerous core elements of gene networks related, for example, to flowering time. https://nph.onlinelibrary.wiley.com/doi/10.1111/nph.18634.
#adaptation #climatechange #popgen #genetics #WGS #evolution #wildtomato #Solanaceae #openaccess
PopgenTUMNov 18, 2022
Recent collaboration with colleagues at #TUM Mathematics and Social Sciences: Echo chambers and opinion dynamics explain the occurrence of vaccination hesitancy. https://doi.org/10.1098/rsos.220367. #MathematicalModeling #infectiousdiseasemodeling
Echo chambers and opinion dynamics explain the occurrence of vaccination hesitancy | Royal Society Open Science

Vaccination hesitancy is a major obstacle to achieving and maintaining herd immunity. Therefore, public health authorities need to understand the dynamics of an anti-vaccine opinion in the population. We introduce a spatially structured mathematical model ...

Royal Society Open Science
PopgenTUMNov 18, 2022
Our latest: Simultaneous Inference of Past Demography and Selection from the Ancestral Recombination Graph under the Beta Coalescent. https://www.biorxiv.org/content/10.1101/2022.09.28.508873v1
#deeplearning #populationgenetics
PopgenTUMNov 18, 2022
What is the carbon footprint of research? We are in the process of doing our assessment for the lab and each published paper! A new tool: https://iopscience.iop.org/article/10.1088/2634-4505/ac84a4