Moritz Negwer

1,096 Followers
2.9K Following
15.1K Posts

Neuroscientist by training, tinkerer by nature. Now scanning transparent mouse brains with light-sheet microscopes. Microscopy, clearing, data crunching, tinkering.

Working as postdoc at @radboudumc with Nael Nadif Kasri and Corette Wierenga, looking at neuron-distribution differences in mouse models of ASD.

Married, father of two. Toots in English, German, Dutch. Boosts a lot.

opted into tootfinder for full-text indexing. Check it out: https://www.tootfinder.ch/index.php?join=1

The ‘crazy rule-defying’ genes that determine biological sex

“In her book ‘Sex, Genes and Chromosomes’, geneticist Jennifer Graves leads readers through “one of the great detective stories of genetics”: the hunt for the genes that determine sex in vertebrates.

Graves makes an ideal guide, having contributed to many of the advances she describes.

With clear explanations, it should be a standard reference on X- and Y-chromosome biology.”

https://www.nature.com/articles/d41586-026-01101-x

The ‘crazy rule-defying’ genes that determine sex

A gripping account reveals the workings of the remarkable chromosomes that specify male or female development.

"FORRT is excited to launch the Open Research Games Portal – a crowdsourced, pedagogically informed database of games and interactive activities for teaching open and reproducible research practices."

https://forrt.org/games/

En we hebben een... website! Op https://zwartboekaanbesteden.nl staat alles wat ik zelf zou kunnen verzinnen wat jullie dan weer zouden kunnen willen vragen aan het Zwartboek Aanbesteden. Heb je zelf een échte vraag? Plaats hieronder een reactie, wie weet heb ik het antwoord.
Zwartboek Aanbesteden ICT

Uitleg over het Zwartboek Aanbesteden ICT op Mastodon.

By now, all eleven of my country 🚂 #train diagrams have been updated for 2026! Represented are: 🇦🇹🇧🇪🇩🇰🇫🇮🇫🇷🇩🇪🇱🇺🇳🇱🇳🇴🇸🇪🇨🇭 I really enjoy updating the diagrams; however, I'm also glad when I've finished. I have become quicker, but it still takes a lot of effort. I hope they help you plan your spring, summer or autumn holiday tour through central or northern 🇪🇺 #Europe or whatever you need them for. 😊
👉️ You find the 2026 rail diagrams on my website: https://larstransportmaps.com/

first impressions of the Lego smart brick, before I do any actual tearing down: wow, I forgot how good they are at working with plastic. the injecton molding remains impeccable, at least for this specific piece (I know about their recent QC issues elsewhere)

it's hard for me to look at the positively microscopic (I am literally using a microscope to look at it) "Li-Ion" lettering and think of anything but "showing off!"

(treehouse doesn't let me attach the full size images, you can grab them here: front, side)

New! Interactional foundations for critical AI literacies https://zenodo.org/records/19452872

Why do Anthropic engineers talking to Claude sound like Azande witch doctors addressing their potions? What does Mambila spider divination have in common with prompt engineering? Why are LLMs so irresistible to interact with?

If you're interested in questions like that, and in luminaries like Lovelace, Adorno, Suchman and Weizenbaum, you may be interested in this paper: https://doi.org/10.5281/zenodo.19452872

It will come as no surprise that ‘to live’ is etymologically related to ‘life’ and ‘alive’.

However, these words are also related to ‘to leave’ and German ‘bleiben’ (“to stay”), which used to have an English cognate: ‘to belive’.

Even ‘lipo-’ in ‘liposuction’ is related, as are the parts ‘-lev-’ and ‘-lv-’ of the numerals ‘eleven’ and ‘twelve’.

All of these words stem from a common Proto-Indo-European root meaning “to stick”.

Click my new graphic to learn all about this word family:

POV: you’re a professor in the Netherlands and you receive a notification that your exams have been printed.

#AcademicMastodon #AcademicChatter #ProfessorLife #Bike #bicycling #Netherlands

Was für eine bahnbrechende Idee: wenn man Gentherapie mit CRISPR-Cas9 als ‚Operation‘ betrachtet und nicht als Medikament, fallen klinische Studien weg und die Behandlung seltener genetischer Krankheiten könnte schneller und viel billiger stattfinden. Die Pharmaindustrie ist nicht darauf ausgerichtet, Behandlungen für seltene Krankheiten zu entwickeln, weil es zu teuer ist. (Gift link)
#gentherapie #RareDiseases #crispr
https://www.nytimes.com/2026/04/09/opinion/genetic-editing-diseases-health-care.html?unlocked_article_code=1.Z1A.Bag2.7kRcnZyDa2s3&smid=nytcore-ios-share

"In the UK, a quarter of total university income is generated by international students, who pay much higher fees than home students. To attract them, British universities rely on vast, largely unregulated networks of agents operating primarily in Asia and Africa."

"The reason British universities spend so much to attract international students is simple: if they were to rely solely on home students, they would go bust."

What could possibly go wrong ... with university finances. This system is not well-grounded, not reliable or stable in any way or form.

https://www.theguardian.com/education/ng-interactive/2026/apr/07/brutal-reality-of-life-as-a-foreign-student-in-the-uk

#UK #academia

‘I see it as trafficking’: the brutal reality of life as a foreign student in the UK

The long read: Universities in Britain rely on overseas applicants paying full fees, which has given rise to some unscrupulous recruiters and left many hopefuls and their families deep in debt

The Guardian