Alex Crits-Christoph

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485 Following
1.2K Posts

Microbiologist.

I'm posting more at bsky.app/profile/acritschristoph.bsky.social than on here these days.

Google Scholarhttps://scholar.google.com/citations?user=UTO7XJwAAAAJ&hl=en&oi=ao
GitHubhttps://github.com/alexcritschristoph

Read this preprint from Manon Berger, Lester Kwiatkowski, Laurent Bopp, and me about how if you consider iron limitation, growing seaweed doesn’t work as a CO₂ removal (CDR) technique.

https://cdrxiv.org/preprint/385

Efficacy of seaweed-based carbon dioxide removal reduced by iron limitation and nutrient competition with phytoplankton – CDRXIV

Carbon dioxide removal (CDR) is a crucial component of climate change mitigation strategies, and ocean afforestation via seaweed cultivation has been touted as a promising marine CDR (mCDR) approach due to high productivity and favorable carbon-to-nutrient ratios. However, global mCDR models generally overlook iron limitation, a potential bottleneck for sustainable seaweed cultivation. While competition with phytoplankton for nutrients could even reduce ocean carbon uptake. Here we assess the potential for this unintended consequence using an ocean biogeochemical model. We find that iron limitation reduces afforestation potential three-fold after already accounting for N and P limitation. Variations in nutrient dynamics contribute to substantial uncertainty in projections of CDR efficiency, with global CDR efficiency ranging from -43% to +78%. This study underscores the need for iron dynamics to be included in projections of ocean afforestation. Failing to account for such nutrient dynamics risks overestimating the efficacy of seaweed-based CDR as a mitigation strategy.

My American friends: I hope you join me today.
To stand up for our freedom to assemble & our freedom of speech. To reject authoritarianism & dictatorship.
To demand the government be accountable to the people - not the reverse.

#NoKings #NoKingsDay #NoKingsProtest

Talking Climate is now a podcast! Every week, you can listen to the good news, not-so-good news, and what you can do on Spotify and Substack, narrated by the amazing Anne Cloud from Voice Over For The Planet.

Whether you're commuting, doing chores around the house, or even if you're just tired of looking at a screen, this new podcast version is for you. My hope is that having an audio version makes it easier than ever to stay informed and inspired.

We’ve already got nine episodes ready to binge — please enjoy, and let me know what you think!

Listen on Spotify: https://open.spotify.com/show/583MdhAsDvn46YcPpvOJkR?si=59acbdf0ee0b4a35
Listen on Substack: https://www.talkingclimate.ca/podcast

Coming soon to all of your favorite podcast platforms.

Climate misinformers focus on the stats that we don't predict will change, e.g., number of landfalling hurricanes.

See the post here: https://www.theclimatebrink.com/p/climate-change-is-making-hurricanes-caf

Climate change is making hurricanes more destructive

a lot of climate misinformers don't want you to understand this

The Climate Brink
We often hear folks skeptical of climate change claim that "the climate is always changing" or "temperatures rise before CO2" or "its the sun!". In a new episode of PBS's Weathered, Jessica Tierney and I try and address these questions: https://www.youtube.com/watch?v=iP2lH2EEr9I
The REAL STORY of Climate Skeptics New Favorite Graph

YouTube

Prevalence and Dynamics of Genome Rearrangements in Bacteria and Archaea

https://www.biorxiv.org/content/10.1101/2024.10.04.616710v1.abstract

#genomics #bacteria #archaea #evolution

Prevalence and Dynamics of Genome Rearrangements in Bacteria and Archaea

The genetic material of bacteria and archaea is organized into various structures and set-ups, attesting that genome architecture is dynamic in these organisms. However, strong selective pressures are also acting to preserve genome organization, and it remains unclear how frequently genomes experience rearrangements and what mechanisms lead to these processes. Here, we assessed the dynamics and the drivers of genomic rearrangements across 121 microbial species. We show that synteny is highly conserved within most species, although several species present exceptionally flexible genomic layouts. Our results show a rather variable pace at which genomic rearrangements occur across bacteria and archaea, pointing to different selective constraints driving the accumulation of genomic changes across species. Importantly, we found that not only inversions but also translocations are highly enriched near the origin of replication ( Ori ), which suggests that many rearrangements may confer an adaptive advantage to the cell through the relocation of genes that benefit from gene dosage effects. Finally, our results support the view that mobile genetic elements—in particular transposable elements—are the main drivers of genomic translocations and inversions. Overall, our study shows that microbial species present largely stable genomic layouts and identifies key patterns and drivers of genome rearrangements in prokaryotes. Significance statement Bacterial and archaeal genomes display stable architectures which ensures the preservation of fundamental cellular processes. However, large genomic rearrangements occasionally occur. Although most of these events are thought to be highly deleterious, they have the potential to lead to adaptive events. Here, we examined the general trends of the dynamic of prokaryotic genomes by exploring the occurrence of genome rearrangements across a broad diversity of bacterial and archaeal species. We find that genomes remain highly syntenic in most species over short evolutionary timescales, although some species appear particularly dynamic. Rearrangements are strongly biased, and most gene blocks are relocated near the origin of replication. We also measured remarkably variables rates at which genome rearrangements occur across species, and transposons and other mobile genetic elements appear to be the main drivers of these variations. Overall, this study provides a comprehensive picture of the dynamic of genome architecture across many microbial species. ### Competing Interest Statement The authors have declared no competing interest.

bioRxiv
High metabolic versatility and phenotypic heterogeneity in a marine non-cyanobacterial diazotroph https://www.cell.com/current-biology/fulltext/S0960-9822(25)00568-8?rss=yes&utm_source=dlvr.it&utm_medium=mastodon

Excited to announce the start of ARTIC2! 🎉

ARTIC2 builds on the success of ARTIC aiming to make sequencing more equitable and accessible. 🤝🧬

EVE Group at Swiss TPH is a key team member - we'll be helping make sequences easier to store and share via Loculus & @pathoplexus ! 🌎

More info in the link! 👀👇🏻
https://www.birmingham.ac.uk/news/2025/ambitious-project-to-develop-low-cost-genome-sequencing-for-pathogens-known-and-unknown

Ambitious project to develop low-cost genome sequencing for pathogens known and unknown - University of Birmingham

Project will build on research that helped diagnostic labs to adopt sequencing capacity for COVID-19 and permit characterisation of future infectious threats

University of Birmingham
Global temperature over the past two years have been very much on the high end of the range of future warming expected in a current policy-type scenario (SSP2-4.5) in the most recent IPCC report (which, itself, expects some near-term acceleration):

We found a really cool giant virus inside the genome of a green alga, and it has a very strange infection cycle that is hard to detect.

There are reports going back decades of viral particles spontaneously appearing in pure cultures of green algae, so this phenomenon seems quite common but mostly overlooked.

https://www.science.org/doi/10.1126/science.ads6303

#viruses #microbiology #algae