☕ Whenever I drink #coffee it just makes me TIRED.
Yet I inexplicably keep trying...hoping for that mythical "energy boost" I've heard tell of.
Any other #ADHD #AuDHD #ActuallyAutistic #neurodivergent folks out there experience this with #caffeine ?
When I was aimlessly studying biochemistry, one thing stuck with me:
On its own, caffeine does nothing.
What Caffeine does is, it blocks the deactivation of the signal that adrenaline lights up.
So, in order to get "energy" out of coffeine, get yourself an adrenaline boost while it's in your system.
I have a method, I can share if there is interest.
@androcat @EmilyMoranBarwick @actuallyautistic @actuallyadhd
Really?!!! Do you happen to have some accessible source material you can point me to - I would love to learn more about how caffeine operates.
@GTMLosAngeles Well balls...I did a bulk-closing of tabs to try and get myself back to "work focus" (ha!)
But I can re-dig. When you say "accessible source material", what do you mean? Like fulltext? Written at a more lay-audience level? Etc?
I can re-investigate & aim more specifically for what you're meaning. Then can private message you the links later.
I don't have a link to the specific bit (it was in a textbook, and it's been 20 years) - here is a link to something like it : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4373791/#:~:text=Caffeine%20binds%20to%20a%20site,the%20one%20blocked%20by%20ryanodine.
The method for producing an adrenaline spike on demand that I use requires a strong wall (like a brick wall or load-bearing wall).
Stand with your back to the wall at a distance of like 20 cm (experiment, ymmv), close your eyes, and then let yourself fall backwards towards the wall.
[Edited to add:Obviously, you should aim to catch your fall on the widest part of the upper back/shoulder area, not your head or your neck. It ought to come naturally to do it that way, but one never knows.]
You will experience a split-second of free-fall before the wall stops you, and your brain will release adrenaline, which again raises the Cyclical-AMP flag, and Coffeine stops the C-AMP flag from being lowered unti it wears off.
Let me know if its useful, it's a hack I developed ages ago, and I haven't needed to pull any all-nighters for a long time, so haven't used it in an equally long time.
@EmilyMoranBarwick @actuallyautistic @actuallyadhd
The behavioral effects of caffeine appear likely to be due in large measure to antagonism of the action of endogenous adenosine at A[1] - and A[2a] -receptors in the central nervous system. Other biochemical mechanisms of action of caffeine, such as release ...
@androcat @GTMLosAngeles @EmilyMoranBarwick @actuallyautistic @actuallyadhd
Makes me wonder about the old trick of falling asleep 😴 with a glass in your hand.. only to let it hit the floor when you fall asleep. May want a heavy glass mug for this experiment…
Thanks for sharing the information… cheers have a wonderful week!
@androcat @GTMLosAngeles @EmilyMoranBarwick @actuallyautistic @actuallyadhd
Hmm - I always drink decaf because regular coffee gives me a too strong & sickening & jittery a rush. BUT ... the most memorably awful occasions have always been when having coffee whilst visiting humans (i.e. flight or fight mode activating).
But now & then I've needed to drink a cup of regular coffee in a quiet space & haven't been as badly affected.
This sounds like a potential explanation as to why.
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