Let's be clear. SARS-CoV-2 is an atrociously bad virus. It can damage any number of organ systems, increases risk for all kinds of illnesses, and is causing a mass disabling event. And that's just what we know about it so far. You do not want to get it, and if you've had it you don't want it again.

1/

Unfortunately, leaders, public health officials, and the large majority of the population think it's over and have deemed continued mitigation measures to be unnecessary. The most vulnerable have no choice but to be very cautious and they are being left behind. Many others are doing their best in order to protect themselves and others, but are also in an impossible situation.

2/

Things are complex and dynamic, everyone's lived experience is different, and most folks who remain COVID aware are trying to balance many different and often conflicting priorities. We're often the lone masker indoors, or the ones declining to attend crowded events, or asking our kids to keep wearing their masks in school, or monitoring what information we still have available and trying to make evidence-based decisions for our families.

3/

My concern is that all or nothing will mean nothing for all. So in practical terms that means we need to support and empower and encourage the people who are still doing what they can. For that reason, much of what I am saying now is aimed at the people who wonder if they can and should keep being cautious (yes and yes) even if they can't do it perfectly or they have to balance other things (like work, kids, family and friendship, mental health).

4/

Every bit that we each do is important, but ultimately we aren't going to succeed if our approach relies on individual choices. For that reason I am also focused more on the need for structural improvements like clean indoor air (ventilation, filtration, UV, air quality reporting), wastewater monitoring, genomic surveillance, and vaccines that are not just chasing variants.

We won't all agree on strategic priorities, but I do believe we all share many of the big picture concerns and goals.

5/

@TRyanGregory All is perfectly said !

Same shit in the fan in France 🇫🇷  : no more public health, even no more monitoring anyware, it’s only wet finger in the wind and good luck everybody.

But, with an covid infection every 2 ou 3 months, nobody can’t have enough chance to expect still healthy in short time.

It’s so bad and we are so few and isolated people who knows counting in a geant covid’s party !

So, yes, we try to make the best we can in the worst we live.

@Monolecte @TRyanGregory This pandemic was the end of effective public health. Public health organizations now are merely other government departments delivering the message of who's in power.

@human3500 @TRyanGregory

Sadly true.

We had the project to write a book about the sociological and political effects of covid on our society, but the editor said : “who cares about covid anymore? We just want to move on!”.

No analysis no reflexion, no thinking…

@Monolecte @human3500 @TRyanGregory and I bet you just like with all the crippled into disablility WW1 vets amd American Flu survivors, we'll soon see social darwinism of the late-1930s Germany kind pushed again, denying the existance of #LongCovid, #MECFS and broadly advocating for making people suffer more for #LateStageCapitalism or perish if they can't be exploited with peak efficiency for #WageWork!

@kkarhan @human3500 @TRyanGregory

In 🇫🇷 , it’s already more or less the way…

@kkarhan @human3500 @TRyanGregory

Evil Macron 🇫🇷  : “Hey, why have we all these poeples sick and staying home instead working more to get less money ? Right, then! It's because doctors are too accommodating: so we're going to ban them from signing off sick leave.”

You can see ?

@TRyanGregory The ‘cop out’ (a bucket of meanings) by public officials is summed up with “Its up to each individual to choose when and how to protect themselves”. Based on what: the plethora of misinformation, confusion, & conspirators? “Ask your PCP” is a deflection. Even PCPs are confused. And who trusts the CDC anymore?
What we’ve learned is we never learn, or avoid implementing what we know we should do.
A vet pathologist colleague called the pandemic “a big clusterf*#k”. I tend to agree.

@TRyanGregory Good thread 👍

Another structural improvement needed is at the work place, including i) paid sick leave for workers falling sick and ii) work-from-home arrangements for workers feeling under the weather.

@__icoder__ @TRyanGregory basically what every social system has?

AFAIK the #USA is the only #G8 with 0 days paid sick leave...

@kkarhan @TRyanGregory Well, it seems every bit of improvement has to be contested and earned. It's both depressing and motivating at the same time 😎
@__icoder__ @TRyanGregory worse...
Some #neolib grifters think the "U.S. Model" is actually something to aspire if not import!
@TRyanGregory I once saw a theory that we'll someday look at a "pre-ubiquitous air-filtration era" the same way we look at a pre-plumbing era. I sure hope so.
@TRyanGregory Absolutely! Important to our family and much more as well. I am a retired periodontist and microbiologist, my wife is a pediatric infectious disease specialist still practicing. As a retirement gig, I am an EMT for a local VFD. We look out for family, patients, and coworkers.
@TRyanGregory I repeatedly said, "THIS THING ISN'T SEASONAL!" Just wait until everyone is huddled in from the cold.
@TRyanGregory This is so confusing to me as my personal experience with the 50 or so relatives and friends who have gotten it is that it was not a big deal and everyone is fine. I've not gotten it (that I know of) yet- not sure why as I've gotten somewhat less cautious. I've friends who are more cautious than I am who have gotten it- and, as I said, everyone I know personally (I have a huge family and circle of pals- most of them over 50) has done fine with it- most of them vaxxed (except for a couple of family members that got it early). I'm having trouble figuring out what to think anymore. It's perplexing!
@OldAndCranky @TRyanGregory you get a different picture reading the medical literature then just talking to people. A lot of the disabilities covid causes aren't visible - some, like vascular inflammation, aren't even perceptible without testing until they manifest as heart attack or stroke. And then people are ashamed to talk about them or don't even make the connection with that minor initial infection they had.
@ravenonthill @TRyanGregory I’m sure that’s true- but no one I know has shown up with anything out of the ordinary.
@OldAndCranky @TRyanGregory how would you know unless it's something major and visibly disabling?
@ravenonthill @TRyanGregory I don’t- but these are folks I’m in constant communication with - I’ve a huge family - no one has had any long term issues who got it since being vaccinated.
@OldAndCranky @TRyanGregory that is remarkable. The vaccine improves the odds, both of severe infection and long covid, but I'd expect at least a few long-term sequelae.
@ravenonthill @TRyanGregory Not that I know of- I mean, maybe a year or two from now someone will have some sort of effect that they wouldn't have it they hadn't gotten Covid, but how would we know?

@OldAndCranky @TRyanGregory that's a problem. Improved diagnostic tools may eventually resolve it.

We know that covid increases the risk of heart attack and stroke and it is believed this is due to infection of the endothelial cells which line blood vessels, but it is difficult to attribute any particular heart attack or stroke to covid infection - about the most that can be done is take preventative measures after infection.

@ravenonthill @TRyanGregory What sort of preventative measures?

@OldAndCranky @TRyanGregory as I recall – keep in mind I am not a doctor just an educated laybird – reduce activity levels for perhaps six months after infection and give anticoagulants. I believe I've seen studies showing that anticoagulants reduce post-covid heart attack and stroke.

With post-covid, what to look for is small blood vessel problems, and the most common tests don't show these.

@ravenonthill @TRyanGregory ah. Are doctors generally recommending such things? I’ve not herd that they are.

@OldAndCranky @TRyanGregory For people at risk, the US CDC recommends it. They say not for others. Risk conditions are common and include atherosclerosis, high blood pressure, and diabetes. (There are probably others.) Personally, I think the data indicates that covid infection creates a risk, but that is not yet a standard recommendation. I also don't know how long it will take for this to become part of common medical practice.

https://www.covid19treatmentguidelines.nih.gov/therapies/antithrombotic-therapy/

Antithrombotic Therapy | COVID-19 Treatment Guidelines

Read about the use of drugs to reduce blood clot formation in people with COVID-19.

COVID-19 Treatment Guidelines
@OldAndCranky @ravenonthill @TRyanGregory the sheer number of people in my community dying of heart attacks and strokes in their 50s and early 60s is incredible. The likelihood of correlation between the fact we were the Covid Capital of Scotland in 2020 and then in 2022-23 we're having a massive spike of middle-aged people dying of heart attacks is...well, high. it's so sad and scary.
@tericarol @OldAndCranky @TRyanGregory In a decade or two, I think it's likely we'll see an elevated rate of heart attack among people in their 20s and 30s. ☹️

@OldAndCranky The thing to keep in mind about risk and population is that there *are* going to be groups that are fine. That's statistically normal. And, COVID seems to have some affinity for e.g. certain blood-types.

Many preexisting conditions that COVID makes worse are linked to wealth and geography -- here, poorer folks. And e.g. my SIL from Mozambique has had malaria; so COVID took her out for six+ months because of her weakened kidneys and liver.

@ravenonthill @TRyanGregory

@OldAndCranky The problem is that each infection is a new dice-roll. So while most people came through their first infection, their third or fourth may be a different story. And also as others have pointed out... invisible effects are invisible.

Personally, my thinking and stamina is still not normal, and it's been months since I "recovered." But you might not know that if I didn't say something.

@ravenonthill @TRyanGregory

@TRyanGregory

We had a long discussion with friends today whom we hadn't seen since 2019. When it came to talking about the dangers #C19 still poses, we eventually hit a dead end.

How do you argue with someone who thinks that by now our bodies know very well how to deal with the virus? We tried our best, mentioned #LongCovid, #diabetes and other sequelae. When we were told that we had no idea what #SarsCoV does to you because we never caught it ourselves, we gave up and changed the subject.

@hypnobeard @TRyanGregory I've had it. I almost died. Not breathing is not fun.