A "Pearl" in current issue of PLOS Pathogens, by Jaqueline Dudley

https://doi.org/10.1371/journal.ppat.1011364

The good:

"... APOBECs induce mutations in both viral and host DNA, but it appears increasingly likely that RNA-containing viruses are mutated by cytidine deaminases. These mutations limit viral replication and transmission. APOBEC-mediated changes on host mRNAs in innate immune cells may provide additional short-term adaptations to inhibit viral infections."

1/2