JIPBFeb 5, 2025
#SUMOylation is a reversible posttranslational modification crucial for many essential #biological processes. Huang et al. present a new system for identifying de-SUMOylation enzymes based on a #SynBio approach.
https://doi.org/10.1111/jipb.13838
@wileyplantsci
#PlantSci #JIPB #Arabidopsis #botany #FreeAccess
jobRxivJan 27, 2025

Post-doc on Acute Myeloid Leukemias chemoresistance and SUMOylation CNRS-Fr

CNRS

Post-doc on Acute Myeloid Leukemias chemoresistance and SUMOylation

See the full job description on jobRxiv: https://jobrxiv.org/job/cnrs-27778-sumoylation-and-acute-myeloid-leukemias/?feed_id=91431

#blood_cancers #cancer_biology #leukemia #sumoylation #ScienceJobs #hiring #research
https://jobrxiv.org/job/cnrs-27778-sumoylation-and-acute-myeloid-leukemias/?feed_id=91431

Post-doc on Acute Myeloid Leukemias chemoresistance and SUMOylation CNRS-Fr

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PLOS BiologyJan 8, 2025
ULP-2 is a conserved SUMO protease required for embryonic development in #Celegans, but what does it do? This study shows that ULP-2 controls germline development by regulating #SUMOylation levels (and so activity) of H3K4me3 reader SET-26 #plosbiology https://plos.io/403ixQ5
SUMO-mediated regulation of H3K4me3 reader SET-26 controls germline development in C. elegans

ULP-2 is a conserved SUMO protease required for embryonic development in C. elegans, but its precise function remains unclear. Here, the authors show that ULP-2 controls germline development by regulating the SUMOylation levels of the H3K4me3 reader SET-26, and thus its activity.

Matt WillemsenSep 16, 2023
Key Weakness of COVID-19 Discovered
New research identified that the COVID virus relies on a human post-translation process called SUMOylation for replication, a process similar to that of Influenza A and B. Blocking this process could lead to the development of antiviral medications effective against multiple viruses, including flu, RSV, and Ebola.
https://scitechdaily.com/key-weakness-of-covid-19-discovered/ #Weakness #COVIDー19 #Biochemistry #Influenza #Pharmacology #SUMOylation
Key Weakness of COVID-19 Discovered

A research study found that without key proteins, the virus cannot infect people. Recent research from UC Riverside has identified  COVID’s Achilles heel — its dependence on key human proteins for its replication — which can be used to prevent the virus from making people sick. In a new paper pu

SciTechDaily