Giuseppe Michieli#Serological evidence of concurrent #Lassa virus and #SARS-CoV-2 #exposure in #Ghana- a cross-sectional study, https://etidiohnew.blogspot.com/2025/12/serological-evidence-of-concurrent.html
#Serological insights into #MERS-CoV dynamics of #antibody responses during acute and convalescent phases and their clinical relevance for #diagnostics and immunity, https://etidiohnew.blogspot.com/2025/06/serological-insights-into-mers-cov.html
#Serological analysis in #humans in Malaysian #Borneo suggests prior exposure to #H5 avian #influenza near migratory #shorebird habitats
Source: Nature Communications, AbstractCases of H5 highly pathogenic avian influenzas (HPAI) are on the rise. Although mammalian spillover events are rare, H5N1 viruses have an estimated mortality rate in humans of 60%. No human cases of H5 infection have been reported in Malaysian Borneo, but HPAI has circulated in poultry and…
#Serological analysis in #humans in Malaysian #Borneo suggests prior exposure to #H5 avian #influenza near migratory #shorebird habitats
Source: Nature Communications, AbstractCases of H5 highly pathogenic avian influenzas (HPAI) are on the rise. Although mammalian spillover events are rare, H5N1 viruses have an estimated mortality …
A Computationally Optimized Broadly Reactive #Hemagglutinin and #Neuraminidase #Vaccine Boosts #Antibody-Secreting Cells and Induces a Robust #Serological Response, Preventing #Lung #Damage in a Pre-Immune #Model https://pubmed.ncbi.nlm.nih.gov/39066344/?utm_source=Feedly&utm_medium=rss&utm_campaign=None&utm_content=1LGAx__djGAJ9poBzWGqPtjEbBDtz4ipSRRPUplmgHEyyF_Ihj&fc=None&ff=20240727133152&v=2.18.0.post9+e462414
... the combination of #H2, #H5, #H7, #N1, and #N2 #COBRA #antigens presents a potential for the formulation of a universal influenza virus vaccine.
A Computationally Optimized Broadly Reactive Hemagglutinin and Neuraminidase Vaccine Boosts Antibody-Secreting Cells and Induces a Robust Serological Response, Preventing Lung Damage in a Pre-Immune Model - PubMed
The hemagglutinin (HA) and neuraminidase (NA) surface proteins are the primary and secondary immune targets for most influenza vaccines. In this study, H2, H5, H7, N1, and N2 antigens designed by the computationally optimized broadly reactive antigen (COBRA) methodology were incorporated into an adj …
#Dynamics of #influenza #transmission in vampire #bats revealed by longitudinal monitoring and a large-scale anthropogenic #perturbation, BioRxIV: https://www.biorxiv.org/content/10.1101/2024.07.26.605290v1
Mechanistic #models fit under a Bayesian framework, which enabled joint inference from #serological and #molecular data, showed that common vampire bats maintain BIV independently of the currently assumed fruit bat #reservoir through immune waning and seasonal #transmission pulses.
Large-Scale #Serological #Survey of #Influenza A Virus in South #Korean Wild #Boar (Sus scrofa) https://pubmed.ncbi.nlm.nih.gov/38842623/?utm_source=Feedly&utm_medium=rss&utm_campaign=None&utm_content=1fgJURi2yzLesFml6et0Bb6krzs_FrNIYgPYVFN50JPwVNFg9s&fc=None&ff=20240606155644&v=2.18.0.post9+e462414
Detected subtypes included 23 cases of pandemic 2009 #H1N1, six of human seasonal #H3N2, three of classical swine H1N1, 13 of triple-reassortant swine #H1N2, seven of triple-reassortant swine H3N2, and seven of swine-origin H3N2 variant. Notably, none of the serum samples tested positive for avian IAV subtypes #H3N8, #H5N3, #H7N7, and #H9N2 or canine IAV subtype H3N2.
Large-Scale Serological Survey of Influenza A Virus in South Korean Wild Boar (Sus scrofa) - PubMed
In this comprehensive large-scale study, conducted from 2015 to 2019, 7,209 wild boars across South Korea were sampled to assess their exposure to influenza A viruses (IAVs). Of these, 250 (3.5%) were found to be IAV-positive by ELISA, and 150 (2.1%) by the hemagglutination inhibition test. Detected …
''Our experimental studies showed that these #H3N8 viruses were transmissible in #ferrets, and #serological data suggest that the #human population lacks effective immunological protection against it. With its wide geographical distribution and continuing evolution in chickens, other spillovers to humans can be expected and might lead to more efficient transmission in humans.''
Dumont, R., Richard, V., Lorthe, E. et al. A population-based #serological study of post- #COVID #syndrome #prevalence and #risk factors in #children and #adolescents. Nat Commun 13, 7086 (2022). https://doi.org/10.1038/s41467-022-34616-8