The dance of #organ positioning: A tango of three #proteins.
#BICC1 #ANKS3 #ANKS6 #ribonucleoprotein
https://phys.org/news/2023-09-positioning-tango-proteins.html
In order to keep track of their environment, cells use cilia, antenna-like structures that can sense a variety of stimuli, including the flow of fluids outside the cell. Genetic defects that cause cilia to malfunction and lose their sensory abilities can result in disorders known as "ciliopathies," including polycystic kidney diseases, but they can also disrupt the correct asymmetric positioning of internal organs during embryonic development—what is known as "organ laterality."
Functionalization of #ribonucleoprotein #condensates with #microtubule motors provides new tools for re-directing RNA to centrosomes or the cell periphery
Audrey Cochard, Zoher Gueroui et al
How does #bacterial #RNA #chaperone #Hfq regulate numerous different #mRNAs and processes?
#CryoEM by Tom Dendooven, Ben Luisi and collaborators shows assembly into distinct polymorphic #ribonucleoprotein complexes as basis
Translational regulation by Hfq–Crc assemblies emerges from polymorphic ribonucleoprotein folding