Molecular basis of #influenza #ribonucleoprotein complex #assembly and processive #RNA synthesis

More than 1,000 players are involved when genetic information is translated into proteins. A new German-Israeli research project is now systematically identifying their tasks. #mRNA #Ribonucleoprotein #RNP @Uni_WUE @MeisterLab @WeizmannScience @dfg_public
https://nachrichten.idw-online.de/2024/01/24/networkers-in-cramped-conditions-german-israeli-research-team-investigates-messenger-ribonucleoproteins
Networkers in cramped conditions: German-Israeli research team investigates messenger ribonucleoproteins

More than 1,000 players are involved when genetic information is translated into proteins. A new German-Israeli research project is now systematically identifying their tasks. #mRNA #Ribonucleoprotein #RNP @Uni_WUE @MeisterLab @WeizmannScience @dfg_public
https://nachrichten.idw-online.de/2024/01/24/networkers-in-cramped-conditions-german-israeli-research-team-investigates-messenger-ribonucleoproteins
Networkers in cramped conditions: German-Israeli research team investigates messenger ribonucleoproteins

The dance of organ positioning: A tango of three proteins

In order to keep track of their environment, cells use cilia, antenna-like structures that can sense a variety of stimuli, including the flow of fluids outside the cell. Genetic defects that cause cilia to malfunction and lose their sensory abilities can result in disorders known as "ciliopathies," including polycystic kidney diseases, but they can also disrupt the correct asymmetric positioning of internal organs during embryonic development—what is known as "organ laterality."

Functionalization of #ribonucleoprotein #condensates with #microtubule motors provides new tools for re-directing RNA to centrosomes or the cell periphery

Audrey Cochard, Zoher Gueroui et al

https://www.embopress.org/doi/full/10.15252/embj.2023114106

An unexpected #actin remodeling function for #DCP1-containing processing bodies in plants:
#Proxitome profiling by Panos Moschou and colleagues links these #ribonucleoprotein assemblies to roles at unique plasma membrane subdomains
https://www.embopress.org/doi/10.15252/embj.2022111885

How does #bacterial #RNA #chaperone #Hfq regulate numerous different #mRNAs and processes?
#CryoEM by Tom Dendooven, Ben Luisi and collaborators shows assembly into distinct polymorphic #ribonucleoprotein complexes as basis

Translational regulation by Hfq–Crc assemblies emerges from polymorphic ribonucleoprotein folding

https://www.embopress.org/doi/full/10.15252/embj.2022111129