Mastodawn

Scientists are working to find common links among #younger #adults who develop #rectal #cancer as they reach their 30s and 40s.

It seems the bulk of such cancers leading the surge in cases today are not hereditary. An #exposure to increase the #risk likely occurred in the #1960s or #1970s

https://www.nbcnews.com/health/health-news/rectal-cancer-rates-deaths-rising-millennials-30s-40s-rcna341389

Rectal cancer rates rising rapidly among people in their 30s and 40s: 'A medical crisis'

Deaths from rectal cancer are rising rapidly among younger adults, an alarming trend that is confounding scientists trying to understand why millennials are so hard-hit.

NBC News

Your Autistic Life

Jul 16, 2025

"I'm having my SAT exam next week."

"Oh, the digital SAT?"

"No. The rectal SAT."

#SAT #digital #rectal

Seán Fenian Jun 3, 2024

https://www.gloucestershirelive.co.uk/news/health/new-bowel-cancer-drug-found-9320411

A new #immunotherapy #cancer #drug, GSK's dostarlimab, has been found in a 42-patient clinical trial at Memorial Sloan Kettering Cancer Centre to be 100% effective against mismatch repair deficient (dMMR) #rectal #cancer. Every single one of the 42 trial patients is now in complete #remission.

New bowel cancer drug is found to be 100% effective

The data showed all patients in a trial had a complete response to treatment, with no evidence of tumours on scans

Bristol Live

Howard Smith MD, AM Apr 4, 2024

Consent Needed For Private Parts’ Exams: New federal H&HS requirement for written consent to examinations of sensitive and intimate zones by both licensed professionals and trainees. #informed #consent #pelvic #breast #rectal #prostate #trainees
https://www.instagram.com/p/C5Wn8VVry4R/

European Radiology May 23, 2023

DWI comes out on top when comparing the accuracy of three state-of-the-art #MRI sequences in the detection of extramural venous invasion (EMVI) in locally advanced #rectal #cancer (LARC). (@f_crimi et al., @UniPadova) Filippo Crimì et al., University of Padova)

#EuropeanRadiology

🔗 https://link.springer.com/article/10.1007/s00330-023-09655-4

Diagnostic accuracy of state-of-the-art rectal MRI sequences for the diagnosis of extramural vascular invasion in locally advanced rectal cancer after preoperative chemoradiotherapy: dos or maybes? - European Radiology

Objectives The aim of this study was to determine the accuracy of three state-of-the-art MRI sequences for the detection of extramural venous invasion (EMVI) in locally advanced rectal cancer (LARC) patients after preoperative chemoradiotherapy (pCRT). Methods This retrospective study included 103 patients (median age 66 years old [43–84]) surgically treated with pCRT for LARC and submitted to preoperative contrast-enhanced pelvic MRI after pCRT. T2-weighted, DWI, and contrast-enhanced sequences were evaluated by two radiologists with expertise in abdominal imaging, blinded to clinical and histopathological data. Patients were scored according to the probability of EMVI presence on each sequence using a grading score ranging from 0 (no evidence of EMVI) to 4 (strong evidence of EMVI). Results from 0 to 2 were ranked as EMVI negative and from 3 to 4 as EMVI positive. ROC curves were drawn for each technique, using histopathological results as reference standard. Results T2-weighted, DWI, and contrast-enhanced sequences demonstrated an area under the ROC curve (AUC) respectively of 0.610 (95% CI: 0.509–0.704), 0.729 (95% CI: 0.633–0.812), and 0.624 (95% CI: 0.523–0.718). The AUC of DWI sequence was significantly higher than that of T2-weighted (p = 0.0494) and contrast-enhanced (p = 0.0315) sequences. Conclusions DWI is more accurate than T2-weighted and contrast-enhanced sequences for the identification of EMVI following pCRT in LARC patients. Clinical relevance statement MRI protocol for restaging locally advanced rectal cancer after preoperative chemoradiotherapy should routinely include DWI due to its higher accuracy for the diagnosis of extramural venous invasion compared to high-resolution T2-weighted and contrast-enhanced T1-weighted sequences. Key Points • MRI has a moderately high accuracy for the diagnosis of extramural venous invasion in locally advanced rectal cancer after preoperative chemoradiotherapy. • DWI is more accurate than T2-weighted and contrast-enhanced T1-weighted sequences in the detection of extramural venous invasion after preoperative chemoradiotherapy of locally advanced rectal cancer. • DWI should be routinely included in the MRI protocol for restaging locally advanced rectal cancer after preoperative chemoradiotherapy.

SpringerLink

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stefania maurizi May 12, 2023

3. The suffragette,who won our rights,extensively relied on hunger strike.The Holloway Brooch, reminds us the horror of #Holloway prison where suffragettes were brutally tortured and force-fed,even via vagina.A century, later #rectal feeding was used against Guantanamo detainees