StructuralBiologyCrystallographic evidence is presented for a putative disulfide molecular switch sensitive to the binding of BIA ligands in the opium poppy latex protein PR10-10 #XRayCrystallography #LigandCoupledConformationalChanges #ProteinStructureAndFunction https://t.co/JacXTgOW9Q
Structural analysis of a ligand-triggered intermolecular disulfide switch in a major latex protein from opium poppy
Crystal structures of two cysteine-to-serine mutants of PR10-10 help to reveal how a ligand-induced conformational change is coupled to the formation of intermolecular disulfide bonds in plant pathogenesis-related family 10 proteins involved in the biosynthesis of benzylisoquinoline alkaloids.
Folmer
Monika