KillBait News5d ago

Structural Changes in Blood Proteins Could Enable Early Detection of Alzheimer’s Disease

📰 Original title: A surprising blood protein pattern may reveal Alzheimer’s

🤖 IA: It's not clickbait ✅
👥 Usuarios: It's not clickbait ✅

View full AI summary: https://killbait.com/en/structural-changes-in-blood-proteins-could-enable-early-detection-of-alzheimers-disease/?redirpost=49afce0e-391d-42a6-bd7a-829c3952b1e9

#health #alzheimers #bloodtest #proteinstructure

Structural Changes in Blood Proteins Could Enable Early Detection of Alzheimer’s Disease

Researchers at Scripps Research Institute have developed a novel blood test that may detect Alzheimer’s disease earlier than current methods by analyzing subtle structural changes in proteins rather…

KillBait Archive
KillBait5d ago

Structural Changes in Blood Proteins Could Enable Early Detection of Alzheimer’s Disease

📰 Original title: A surprising blood protein pattern may reveal Alzheimer’s

🤖 IA: It's not clickbait ✅
👥 Usuarios: It's not clickbait ✅

View full AI summary: https://killbait.com/en/structural-changes-in-blood-proteins-could-enable-early-detection-of-alzheimers-disease/?redirpost=49afce0e-391d-42a6-bd7a-829c3952b1e9

#health #alzheimers #bloodtest #proteinstructure

Structural Changes in Blood Proteins Could Enable Early Detection of Alzheimer’s Disease

Researchers at Scripps Research Institute have developed a novel blood test that may detect Alzheimer’s disease earlier than current methods by analyzing subtle structural changes in proteins rather…

KillBait Archive
sayzardFeb 11

Wes Roth (@WesRoth)

Isomorphic Labs가 차세대 약물 설계 엔진 'IsoDDE'를 공개함. IsoDDE는 AlphaFold 3보다 단백질-리간드 구조 예측 정확도를 두 배 이상 향상시켰다고 하며, AI 기반 약물 설계와 신약 발견 분야의 새로운 전기를 예고함.

https://x.com/WesRoth/status/2021539720899985589

#isomorphiclabs #isodde #drugdesign #proteinstructure

Wes Roth (@WesRoth) on X

Isomorphic Labs just unlocked the next frontier of AI-driven drug design. Isomorphic Labs has unveiled the IsoDDE, its next-gen Drug Design Engine that goes far beyond AlphaFold 3. IsoDDE more than doubles AF3’s accuracy on protein-ligand structure prediction in novel systems,

X (formerly Twitter)
TechLİfeDec 24

AI Transforms Scientific Discovery: How AlphaFold and AI Co-Scientist Are Reshaping Research

https://techlife.blog/posts/ai-transforms-scientific-discovery-alphafold-ai-co-scientist/

#AlphaFold #Google #DeepMind #ScientificDiscovery #ProteinStructure #Gemini #NobelPrize #AIResearch #AlphaEvolve #BioNeMo #AI

AI Transforms Scientific Discovery: How AlphaFold and AI Co-Scientist Are Reshaping Research

From solving the 50-year protein folding problem to generating research hypotheses in hours, AI tools like AlphaFold and Google's AI Co-Scientist are compressing discovery timelines from years to days

TechLife
andie Nov 26
My PhD research proposal is nearly done after over a month of working on it full tilt. Been an incredible (re)learning experience! Feel so much more comfortable with producing academic style writing again. Had some mega size cobwebs to dust off there. 🕸 Helps to have had to read so many journal articles to grok it all and connect the dots.

Excited to start reaching out to programs and lab heads! ​​ If you happen know folks here on mastodon that are involved in Computational Biology or Biophysics program please drop names in replies or boost for reach. Looking to connect!

Now to treat myself to a much needed rest day and massage for my keyboard-warped back and tired eyed. ♨️
#research #compBio #proteinStructure #molecularDynamics #bioPhysics
CSBJNov 20

💊 Can understanding receptor bias help us design safer, more selective GPCR drugs?

🔗 Biased activation of the vasopressin V2 receptor probed by molecular dynamics simulations, NMR and pharmacological studies. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2024.10.039

📚 CSBJ: https://www.csbj.org/

#GPCR #StructuralBiology #MolecularDynamics #NMR #Pharmacology #ProteinStructure #DrugDiscovery #ComputationalBiology #CellSignaling

David Aragão 🔶Nov 14

Excited to announce the BCA Biological Structures Group (BSG) 2025 Winter Meeting!

This is a fantastic opportunity for researchers in our field to connect and explore the theme of "New Advances and Future Directions in Structural Biology".

🗓️ Date: Friday, 12th December 2025
📍 Location: Dorothy Crowfoot Hodgkin Building, University of Oxford
🔬 Time: 10:30 - 18:00

We have an outstanding lineup of confirmed speakers from both academia and industry:
- Chun-wa Chung (GSK)
- Josie Ferreira (UCL)
- Chris Hill (University of York)
- Yvonne Jones (University of Oxford)
- Christos Pliotas (University of Manchester)
- Neil Ranson (University of Leeds)

In addition to these brilliant talks, there will be a poster session with prizes for outstanding presentations—a great chance for early-career researchers to showcase their work!

Register here:
https://www.oxforduniversitystores.co.uk/product-catalogue/biochemistry/events/structural-biology-meeting-2025-oxford

View the full programme:
https://www.bioch.ox.ac.uk/sitefiles/bca-meeting-2025.pdf

Deadline for poster talk consideration: 28th November 2025

To learn more about the BCA's Biological Structures Group, visit our website:
https://bsg.crystallography.org.uk/

#StructuralBiology #Crystallography #BSG #BCA #WinterMeeting #Oxford #Biophysics #CryoEM #DrugDiscovery #Networking #Science #Academia #Industry #ProteinStructure

Structural Biology Meeting 2025 - Oxford | University of Oxford

Registration fee to attend the Structural Biology Meeting 2025, to be held at the Dorothy Crowfoot Hodgkin Building in Oxford, on Friday 12th December 2025

CSBJNov 13

🧫 What secret molecular choreograph helps bacteria stay resilient against antibiotics and detergents?

🔗 Coordinated subdomain movements of MlaC regulate ligand binding and transport. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.05.031

📚 CSBJ: https://www.csbj.org/

#Microbiology #AntibioticResistance #MembraneBiology #StructuralBiology #ComputationalChemistry #MolecularDynamics #ComputationalBiology #Biophysics #ProteinStructure #DrugDiscovery #MolecularDocking

michaelSep 19

16-Sep-2025
Better understanding of #bitter #taste receptors: An AlphaFold3-based structure study
Researchers use an advanced AI-based prediction model, #AlphaFold 3, to predict the structure of human bitter taste #receptors
https://www.eurekalert.org/news-releases/1098406

#science #humans #physiology #proteinstructure

Better understanding of bitter taste receptors: An AlphaFold3-based structure study

Taste receptors are specialized proteins that facilitate the sense of taste. There are different groups of receptors for detecting different tastants. Understanding the structure of these receptors will help in elucidating their function. 25 different bitter taste receptors have been identified to date, out of which the 3D crystal structures of only three have been characterized. In this study, the researchers use an artificial intelligence-based structure prediction model to characterize the structure of these receptors.

EurekAlert!
CSBJAug 28, 2025

🌀 Could a protein that twists into filaments reveal how cells keep themselves in balance?

🔗 Cryo-EM structure of AAA + ATPase thorase reveals novel helical filament formation. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.05.018

📚 CSBJ: https://www.csbj.org/

#StructuralBiology #CryoEM #Thorase #MolecularBiology #mTORC1 #ProteinStructure #Biophysics #AAAplusATPase #SynapticPlasticity #Mitochondria