Psychotherapy Commission ACPEFeb 12

Of note to psychotherapists, social workers, and other mental health professionals, this report highlights a biological mechanism that may influence cognitive aging. Researchers describe a protein, DMTF1, whose enhancement may restore the regenerative capacity of neural stem cells, supporting memory and learning despite age-related damage. Such findings broaden the understanding of brain aging and point toward potential future interventions that slow or reverse aging-related cognitive decline.

Article Title: Scientists discover protein that rejuvenates aging brain cells

Link to Science Daily Mind-Brain News: https://ift dot tt/q2O96AQ

#neuroscience #brainaging #neuralstemcells #DMTF1 #cognitivehealth

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PLOS BiologyJul 31, 2025
#NeuralStemCells (NSCs) & ependymal cells (ECs) are derived from #RadialGlialCells. This study uses #scRNAseq to characterize cell fate trajectories in the developing #VentricularZone, identifying TFEB as a regulator of the NSC/EPC balance @PLOSBiology https://plos.io/3HbrsJG
PLOS BiologyJul 30, 2025
Quiescent hippocampal #NeuralStemCells (NSCs) support #neurogenesis in adulthood. This study shows that NSCs have different levels of quiescence & that Sox5 controls the balance between shallow & deep quiescence during hippocampal development @PLOSBiology https://plos.io/44Su34u
PLOS BiologyApr 4, 2025
Quiescent #NeuralStemCells (qNSCs) in the adult mouse SVZ have a limited capacity to generate #glia. This study shows that a subpopulation of multipotent qNSCs with high Gas1 expression can produce #oligodendrocytes throughout life & after demyelinating injury @PLOSBiology https://plos.io/4iY4nbh
Gas1-high quiescent neural stem cells are multipotent and produce oligodendrocytes during aging and after demyelinating injury

Quiescent neural stem cells (qNSCs) in the adult mouse subventricular zone are known to contain a limited capacity to generate glia. In this study, the authors identify a subpopulation of multipotent qNSCs, distinguished by high Gas1 expression, with a higher propensity to produce oligodendrocytes throughout life and after demyelinating injury.

Regenerative Research Fdn/NSCISep 9, 2024

🔬Its been 17 years since Dr. Sally Temple and Dr. Jeffrey Stern opened the first independent stem cell research institute in the country! Since opening, they have continued to foster the successful translation of neural stem cell discoveries to therapeutics!

Learn more about our institution and ongoing research at https://zurl.co/sBj9

#stemcellresearch #neuralstemcells #agerelatedmaculardegeneration #alzheimersdisease #parkinsonsdisease #spinalcordinjury

Homepage - Neural Stem Cell Institute, Rensselaer NY

Neural Stem Cell Institute, Rensselaer NY
EMBO Mol. MedicineApr 11, 2023

🐣 Our April issue is online today!

This month's cover highlights an article on #ShearStress control of vascular leaks and #atheromas.

Also in this issue: articles on #BreastCancer, #NeuralStemCells, #PrematureOvarianInsufficiency, #Psoriasis, #CLN1, & much more!

🗞️ Fully #openaccess: https://www.embopress.org/toc/17574684/2023/15/4

Regenerative Research Fdn/NSCIDec 20, 2022

In Part 3 of her year-end blog series, Dr. Liz Fisher details publications authored by NSCI scientists in 2022, relating to #neuralstemcells, #neurodegeneration, #organoid and #assembloid nomenclature, #SpinalCordInjury, #intrabody therapeutics and more.

https://neuralsci.org/sharing-science

NSCI Year in Review - Part 3 - Neural Stem Cell Institute, Rensselaer NY

NSCI scientists published numerous studies in high-quality scientific journals related to stem cell research, neuroscience and therapeutics in 2022.

Neural Stem Cell Institute, Rensselaer NY