What are the mechanisms allowing #zebrafish to #regenerate their neurons after spinal cord injury? This study by Alberto Docampo-Seara, Catherine Becker, Thomas Becker &co shows that a protein in #microglia regulates regenerative #neurogenesis in multiple ways

https://plos.io/4xy2CcB

Exercise enhances mood through a muscle-derived protein called apelin that travels to the brain and supports neurogenesis and neural signaling, linking physical activity with improved depressive-like behaviors in animal models. The findings identify a specific molecular pathway by which exercise may influence brain function and mood.

This topic is of interest to psychology because it connects physical activity, brain chemistry, and emotional well-being, highlighting mechanisms behind mood regulation and the potential for non-pharmacological influences on mental health.

Article Title: Scientists discover how exercising muscles communicate with the brain to fight depression

Link to PsyPost Article: https://nolinkpreview.com/www.psypost.org/scientists-discover-how-exercising-muscles-communicate-with-the-brain-to-fight-depression/

#apelin #exerciseandmood #neurogenesis #hippocampus #glutamatergictransmission #APJreceptor #CaseinKinase2 #neuralplasiticity #myokines #depressionresearch

Why the lack of neurogenesis in adults may be an evolved positive trait in mammals. In song birds:

“... as the new neurons move through the brain, they seem to be pushing or deforming the tissue,” Scott says. “You could imagine that they might be altering the circuit, breaking connections that are the basis of stored memories.”

https://www.scientificamerican.com/article/songbirds-reveal-the-dark-side-of-making-new-brain-cells-as-adults/

Commentary on:

"Songbird connectome reveals tunneling of migratory neurons in the adult striatum", Shvedov et al. 2026
https://dx.doi.org/10.1016/j.cub.2026.03.057

#neuroscience #songbirds #zebrafinch #neurogenesis

Songbirds reveal the dark side of making new brain cells as adults

A new study in songbirds might help explain why humans don’t generate many new brain cells, called neurons, as adults

Scientific American

The article discusses recent findings showing that adult human brains continue to generate new neurons, with superagers displaying particularly active neurogenesis linked to preserved memory and cognitive health. It highlights how chromatin accessibility and specific transcription factors shape this process, and compares healthy aging, mild cognitive impairment, and Alzheimer's disease. The study also points to potential lifestyle and environmental factors that could influence neurogenesis and cognitive aging.

This topic matters to psychology because it connects molecular mechanisms of brain aging with observable cognitive outcomes, illustrating how resilience in memory may arise from distinct cellular and epigenetic profiles. It offers a lens on why some individuals maintain cognitive health into advanced age, informing theories of aging, memory, and brain plasticity.

Article Title: Superager brains excel at something scientists once thought was impossible

Link to PsyPost Article: https://www dot psypost.org/superager-brains-excel-at-something-scientists-once-thought-was-impossible/

Copy and paste broken link above into your browser and replace "dot" with "." for link to work. We have to do it this way to avoid displaying copyrighted images.

#neurogenesis #aging #hippocampus #epigenetics #cognitivehealth

Enhanced Vitamin K Analogues Promote Neuron Regeneration and Neuroprotection

Researchers at the Shibaura Institute of Technology in Japan have developed novel vitamin K analogues that significantly enhance neuron growth and differentiation. By combining vitamin K with retinoic acid, these compounds, particularly one termed 'Novel VK,' demonstrated approximately threefold hig... [More info]

Enhanced Vitamin K Analogues Promote Neuron Regeneration and Neuroprotection

@aibot How might the discovery of the novel vitamin K analogue 'Novel VK' influence future treatments for neurodegenerative diseases like Alzheimer's and Parkinson's, considering its enhanced ability to promote neuron...

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