U01.01.105 G6PD Deficiency: Genetics, Pathophysiology, and Clinical Triggers
Master Glucose-6-Phosphate Dehydrogenase (G6PD) deficiency with our U01.01.105 guide. Understand the X-linked inheritance, the role of oxidative stress, and classic findings like Heinz bodies and Bite cells. Learn the common triggers including fava beans and sulfa drugs. Essential USMLE Step 1 hematology and biochemistry available on mymedschool.org.
U01.01.104 Pentose Phosphate Pathway: G6PD, NADPH, and Ribose-5-Phosphate
Master the Pentose Phosphate Pathway (PPP) with our U01.01.104 guide. Learn about the oxidative and non-oxidative phases, the role of G6PD, and the production of NADPH for reductive biosynthesis and glutathione reduction. Essential USMLE Step 1 biochemistry available on mymedschool.org.
U01.01.103 Gluconeogenesis: The 4 Irreversible Enzymes & Regulation
Master the "bypass" reactions of Gluconeogenesis with our U01.01.103 guide. Learn the four irreversible enzymes: Pyruvate Carboxylase, PEP Carboxykinase, Fructose-1,6-bisphosphatase, and Glucose-6-phosphatase. Understand how the liver maintains blood glucose during fasting for USMLE Step 1. Available on mymedschool.org.
U01.01.102 Electron Transport Chain and Oxidative Phosphorylation: High-Yield Review
Master the final stage of aerobic respiration with our U01.01.102 guide. Explore the complexes (I-IV), the role of Cytochrome C, and the proton gradient powering ATP Synthase. Learn about ETC inhibitors (Cyanide, Carbon Monoxide) and uncouplers (DNP). Essential USMLE Step 1 biochemistry available on mymedschool.org.
U01.01.101 TCA Cycle: Krebs Cycle Steps, Enzymes, and Energy Yield
Master the Tricarboxylic Acid (TCA) Cycle with our U01.01.101 guide. Learn the sequence of reactions, key enzymes like Isocitrate Dehydrogenase, and the total yield of NADH, FADH2, and GTP. Understand how the cycle is regulated by energy charge and its role in aerobic respiration. Essential USMLE Step 1 biochemistry available on mymedschool.org.
U01.01.100 Pyruvate Metabolism: The Four Fates of Pyruvate High-Yield Review
Master the metabolic crossroads of Pyruvate with our U01.01.100 guide. Learn the four major fates of pyruvate: conversion to Acetyl-CoA, Oxaloacetate, Lactate, and Alanine. Understand the enzymes, cofactors, and clinical significance of each pathway for USMLE Step 1. Available on mymedschool.org.
U01.01.098 Pyruvate Dehydrogenase Complex: The Bridge to the TCA Cycle
Master the Pyruvate Dehydrogenase (PDH) complex with our U01.01.098 guide. Explore the three enzymes (E1, E2, E3), the five essential cofactors (B1, B2, B3, B5, Lipoic Acid), and the clinical consequences of PDH deficiency. Learn how arsenic poisoning and thiamine deficiency disrupt this critical metabolic link. Essential USMLE Step 1 biochemistry available on mymedschool.org.
U01.01.098 Pyruvate Dehydrogenase Complex: The Bridge to the TCA Cycle
Master the Pyruvate Dehydrogenase (PDH) complex with our U01.01.098 guide. Explore the three enzymes (E1, E2, E3), the five essential cofactors (B1, B2, B3, B5, Lipoic Acid), and the clinical consequences of PDH deficiency. Learn how arsenic poisoning and thiamine deficiency disrupt this critical metabolic link. Essential USMLE Step 1 biochemistry available on mymedschool.org.
U01.01.097 Fructose-2,6-bisphosphate: The Master Switch of Glycolysis and Gluconeogenesis
Master the pivotal role of Fructose-2,6-bisphosphate (F-2,6-BP) in metabolic regulation with our U01.01.097 guide. Learn how the PFK-2/FBPase-2 bifunctional enzyme complex responds to Insulin and Glucagon to toggle between energy production and glucose synthesis. Essential biochemistry for USMLE Step 1 prep on mymedschool.org.
U01.01.096 Glycolysis Regulation: PFK-1, Pyruvate Kinase & Hormonal Control
Master the complex regulation of Glycolysis with our U01.01.096 guide. Explore the three irreversible steps, the pivotal role of PFK-1, and how Fructose-2,6-bisphosphate acts as the master metabolic switch. Understand the hormonal influence of Insulin and Glucagon on enzyme phosphorylation. Essential preparation for USMLE Step 1 on mymedschool.org.
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