New independent preprint (AI-assisted, fully open + reproducible): a within-host HIV model in which a therapeutic interfering particle coupled to the latent reservoir is predicted to *assist* immune-mediated post-treatment control — extending, not contradicting, Dodd & de Boer (2025). Illustrative modeling hypothesis, not a cure. Read / code / DOI: https://sethc555.github.io/hiv-aids-research/ #HIV #immunology #virology #compbio #mathbio
A reservoir-coupled therapeutic interfering particle can assist immune-mediated HIV-1 post-treatment control: a within-host modeling study

A within-host modeling study: a therapeutic interfering particle (TIP) coupled to latent-reservoir reactivation is predicted to assist immune-mediated HIV-1 post-treatment control — extending, not contradicting, Dodd & de Boer (2025). Illustrative modeling hypothesis, not a cure.

Seth Cope — HIV within-host modeling
Great plenary for this morning at @smbmathbiology.bsky.social by former SMB president and legendary #mathbio person Fred Adler. Burocracy as the way our body tries to stop cancer
#SMB2025
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Book: Mathematics in Biology, by Markus Meister, Kyu Hyun Lee, and Ruben Portugues.
http://www.mathinbio.com/

@mameister4 has a blog entry on why they decided to write the book:
https://markusmeister.com/2025/02/20/why-we-wrote-a-math-book-for-biologists/

Interestingly:

• The web site offers value-added materials, for example sample curricula, and the code for generating every figure in the book.
• The book contains many exercises, but no solutions. We invite student readers to produce such solutions and we will publish the best ones on this site with author credit.

Looks like a long-running project to support and engage the broader community – and it's been 12 years in the making!

#mathematics #mathbio #math #biology

Mathematics in Biology

Chasing the source of an assumption, something that lots of #MathOnco #MathBio people do:

https://www.youtube.com/watch?v=bgo7rm5Maqg

We Fell For The Oldest Lie On The Internet

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Postdoc in computational genomics - Farabella Lab

Istituto Italiano di Tecnologia

????JOB OPENING????
We are hiring #postdoc #compbio #MathBio #bioinfo!

For more info, feel free to DM or visit https://farabellalab.org.

See the full job description on jobRxiv: https://jobrxiv.org/job/istituto-italiano-di-tecnologia-27778-postdoc-in-computational-genomics-farabella-...
https://jobrxiv.org/job/istituto-italiano-di-tecnologia-27778-postdoc-in-computational-genomics-farabella-lab/?feed_id=84618

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The Armenise-Harvard Integrative Nuclear Architecture integrates imaging techniques, genomic data, structural bioinformatics, and physical theories to investigate the 3D genome organisation plasticity and how multiple components of the nucleus influence gene regulation information across scales. We

Postdoc in computational genomics - Farabella Lab

Istituto Italiano di Tecnologia

????JOB OPENING????
We are hiring #postdoc #compbio #MathBio #bioinfo!

For more info, feel free to DM or visit https://farabellalab.org.

See the full job description on jobRxiv: https://jobrxiv.org/job/istituto-italiano-di-tecnologia-27778-postdoc-in-computational-genomics-farabella-...
https://jobrxiv.org/job/istituto-italiano-di-tecnologia-27778-postdoc-in-computational-genomics-farabella-lab/?feed_id=81808

Home

The Armenise-Harvard Integrative Nuclear Architecture integrates imaging techniques, genomic data, structural bioinformatics, and physical theories to investigate the 3D genome organisation plasticity and how multiple components of the nucleus influence gene regulation information across scales. We

Postdoc in computational genomics - Farabella Lab

Istituto Italiano di Tecnologia

????JOB OPENING????
We are hiring #postdoc #compbio #MathBio #bioinfo!

For more info, feel free to DM or visit https://farabellalab.org.

See the full job description on jobRxiv: https://jobrxiv.org/job/istituto-italiano-di-tecnologia-27778-postdoc-in-computational-genomics-farabella-...
https://jobrxiv.org/job/istituto-italiano-di-tecnologia-27778-postdoc-in-computational-genomics-farabella-lab/?feed_id=78266

Home

The Armenise-Harvard Integrative Nuclear Architecture integrates imaging techniques, genomic data, structural bioinformatics, and physical theories to investigate the 3D genome organisation plasticity and how multiple components of the nucleus influence gene regulation information across scales. We

Postdoc in computational genomics - Farabella Lab

Istituto Italiano di Tecnologia

????JOB OPENING????
We are hiring #postdoc #compbio #MathBio #bioinfo!

For more info, feel free to DM or visit https://farabellalab.org.

See the full job description on jobRxiv: https://jobrxiv.org/job/istituto-italiano-di-tecnologia-27778-postdoc-in-computational-genomics-farabella-...
https://jobrxiv.org/job/istituto-italiano-di-tecnologia-27778-postdoc-in-computational-genomics-farabella-lab/?feed_id=77188

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The Armenise-Harvard Integrative Nuclear Architecture integrates imaging techniques, genomic data, structural bioinformatics, and physical theories to investigate the 3D genome organisation plasticity and how multiple components of the nucleus influence gene regulation information across scales. We

Way to start #SMB2024 with friend and mentor @sandy, chair of @mathonco talking about ALL the work his group has led in #AdaptiveTherapies. First keynote talk in this meeting #MathOnco #MathBio