Mastodawn

This Primer explores two @PLOSBiology studies that reveal how short axon cells in the #OlfactoryBulb integrate #cholinergic input from the basal #forebrain to dynamically regulate #olfactory input. Papers: https://plos.io/4pvost3 https://plos.io/3VnO1hT Primer: https://plos.io/3Ivzcqy

PLOS Biology Sep 18, 2025

#DiscriminativeLearning enhances #sensory contrast for rapid, accurate decisions, but how? This study describes a sensory- #forebrain circuit centered on #dopaminergic short axon cells in the mouse #olfactory bulb, which refines sensory input during learning @PLOSBiology https://plos.io/4pvost3

PLOS Biology Sep 18, 2025

Animals can use cues to initiate task preparation and amplify relevant #sensory input, but how? This study describes a circuit whereby an attentional cue triggers #cholinergic #forebrain activity, enhancing #olfactory responses (deactivated upon task-proficiency) @PLOSBiology https://plos.io/3VnO1hT

preLights Dec 8, 2023

Did you see the preLight from Emily Winson-Bushby, Haoming You & Ana Dorrego-Rivas (#GrubbLab)?

They cover a preprint from Elisa Galliano & team that reveals clear functional differences between dopaminergic neurons in the midbrain and forebrain 🧠

#preLight 👉https://prelights.biologists.com/highlights/characterization-of-identified-dopaminergic-neurons-in-the-mouse-forebrain-and-midbrain/

#neuroscience #brain #forebrain #midbrain #dopamine #electrophysiology

Characterization of Identified Dopaminergic Neurons in the Mouse Forebrain and Midbrain - preLights

Are all dopaminergic neurons the same? Lau and colleagues played a round of Spot the Difference with dopaminergic neurons in different brain regions and found two functionally defined groups.

preLights