Cholinergic Receptors Made Easy: Nicotinic and Muscarinic Receptor Functions | USMLE Pharmacology Review

Learn to differentiate nicotinic (Nn, Nm) and muscarinic (M1–M5) receptor functions with this interactive matching activity. Master the key actions involved in synaptic transmission, cardiac control, secretion, and smooth muscle contraction — high-yield for USMLE Step 1.

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This Primer explores two @PLOSBiology studies that reveal how short axon cells in the #OlfactoryBulb integrate #cholinergic input from the basal #forebrain to dynamically regulate #olfactory input. Papers: https://plos.io/4pvost3 https://plos.io/3VnO1hT Primer: https://plos.io/3Ivzcqy
Animals can use cues to initiate task preparation and amplify relevant #sensory input, but how? This study describes a circuit whereby an attentional cue triggers #cholinergic #forebrain activity, enhancing #olfactory responses (deactivated upon task-proficiency) @PLOSBiology https://plos.io/3VnO1hT
Sleep regulation in #Drosophila. @dissel_lab1 &co show that #cholinergic #neurons in the dorsal fan-shaped body (dFB) play a major role in #sleep modulation in this neurochemically heterogeneous region of the fly brain #plosbiology https://plos.io/42uPczp
The dorsal fan-shaped body is a neurochemically heterogeneous sleep-regulating center in Drosophila

The role of the dorsal fan-shaped body in sleep regulation in Drosophila is contested. This study shows that cholinergic neurons in the dorsal fan-shaped body play a major role in sleep modulation in this neurochemically heterogeneous sleep-regulating center in the fly brain.