Mastodawn

New Chip Monitors Cancer Therapy Effectiveness. A micro-fluidic chip can quantitate the cancer-cell killing effectiveness of chemotherapeutic agents against one of the deadliest brain cancers, glioblastoma. #glioblastoma #microfluidics #extracellularparticles #chemotherapy
https://www.instagram.com/p/DSk2I2HFfcj/

Howard G. Smith MD, AM on Instagram: "New Chip Monitors Cancer Therapy Effectiveness A state of the art micro-fluidic chip can quantitate the cancer-cell killing effectiveness of chemotherapeutic agents against one of the deadliest brain cancers, glioblastoma. So say Northwestern University neurosurgical oncologists working in collaboration with University of Michigan bioengineers in a Nature Communications published tudy. Leet’s talks a look at how this chip strategy works. When the albumin-bound paclitaxel chemotherapeutic agent penetrates the blood-brain barrier with the help of focused ultrasound and kills glioblastoma tumor cells, the dying cells release extracellular vesicles and particles into the bloodstream. The novel microchip, named the GlioExoChip, capably captures these released particles permitting their quantitation and the estimation of chemotherapeutic killing effectiveness after each drug infusion. This technique provides a near-immediate estimation of treatment effectiveness with only a blood draw. Compare this with the need to wait months to look for tumor shrinkage on MR imaging. If any given agent is effective, treatment continues. If not, another agent is chosen. Once the precision and specificity of this technique is confirmed in larger clinical studies, the GlioExoChip will become available for routine use. https://www.nature.com/articles/s41467-025-65681-4 #glioblastoma #microfluidics #extracellularparticles #chemotherapy"

A new microfluidic chip, the GlioExoChip, is revolutionizing cancer treatment by providing real-time monitoring of chemotherapy effectiveness. This innovative technology allows for personalized treatment and faster recovery for glioblastoma patients. The GlioExoChip captures extracellular vesicles and particles released by dying tumor cells, enabling healthcare professionals to adjust treatment strategies accordingly. Say goodbye to waiting months for MRI results and hello to a more effective treatment plan. This cutting-edge technology is set to change the face of cancer treatment forever.

Instagram