Importantly, we found that the three conductances shaping #singlecell responses also drove higher #excitability in a #human-like #brain-circuit, as observed in human patients with late-stage #temporal #lobe #epilepsy.
Using light to manipulate neuron excitability

Nearly 20 years ago, scientists developed ways to stimulate or silence neurons by shining light on them. This technique, known as optogenetics, allows researchers to discover the functions of specific neurons and how they communicate with other neurons to form circuits.

Medical Xpress
Changes in #neuron #excitability have been linked to many processes in the #brain, including learning and #aging, and have also been observed in some brain disorders, including #Alzheimer’s disease.
#Neuroscience #sflorg
https://www.sflorg.com/2022/12/ns12072201.html
Using light to manipulate neuron excitability

A new optogenetics-based tool allows researchers to control how neurons respond to electrical input.

Such a cool example of eukaryotic #excitability:
Rapid calcium influx triggered by the presence of mucus induces encystation of the ciliated zoospore of a frog-killing #chytrid fungus
Cilium mediated??
https://www.sciencedirect.com/science/article/pii/S0960982222005759
#BiologistsWorkshops
Lillian Fritz-Laylin @FritzLaylin