Interesting description of heteroresistance to piptaz, but from a highly monitored patient in a clinical trial. And was not associated with treatment failure Most patients don't have post-antibiotic microbiology samples, so maybe this happens commonly (& inconsequentially) #IDSky #ClinMicro #UTISky

RE: https://bsky.app/profile/did:plc:l7hoy6b4k4tuwysko34jriwi/post/3mko2f3cdxc2i
Impressive - @[email protected] now has 10,000 members worldwide! #ClinMicro #AMR #IDSky @[email protected]
Important piece of work that guides much of our OPAT practice in UK. It's also impressive in its acceptance of the evidence. Literally the guideline for use of IV antibiotics is advocating for use of oral antibiotics instead! 👏 #IDSky #ClinMicro #AMR #OPAT

RE: https://bsky.app/profile/did:plc:l7hoy6b4k4tuwysko34jriwi/post/3mk62wkqymc27
A sobering but very important observation about war and antibiotic resistance #IDSky #ClinMicro #AMR

RE: https://bsky.app/profile/did:plc:l7hoy6b4k4tuwysko34jriwi/post/3mjyl3hct3k26
For those that don't know (included me!), Gremubamab binds specifically to the Pseudomonas aeruginosa PcrV protein and the Psl exopolysaccharide. Both are virulence factors used for adhesion and biofilm stability. Thanks @[email protected] ! #ESCMIDGlobal2026 #IDSky #ClinMicro

RE: https://bsky.app/profile/did:plc:jh6ykfvllrvxnubjpzazm2vb/post/3mjr55jvdxc2u
"Among 5121 participants assessed, 1573 (30.7%) underwent DOC, of which 1502 (95.5%) were delabeled." - that's a lot of penicillin allergy mislabelling out there! 😲 However... DOC.. more likely to be prescribed penicillin and less likely WHO “Watch” or “Reserve” antibiotics #IDSky #ClinMicro #AMR

Direct Oral Challenge for Peni...
Direct Oral Challenge for Penicillin Allergy: A Hospital Implementation Evaluation Via the International Network of Antibiotic Allergy Nations (iNAAN) Study

Abstract. In this international, multicenter prospective study, implementing penicillin direct oral challenge (DOC) using a digital toolkit was acceptable,

OUP Academic
We do quite a lot of antibiotic self administration in OPAT. Massive win if it can be achieved - lower requirements on hospital / community nurses & big autonomy win for the patients and their families. #OPAT #IDSky #ClinMicro

RE: https://bsky.app/profile/did:plc:ihlofya6s7dijxbv242tjam6/post/3mhq73irnj22b
The Widal test drives typhoid over diagnosis and, by extension, unnecessary antibiotic prescriptions. Good piece in @[email protected] #IDSky #ClinMicro #AMR

The diagnostic void: how typho...
Well, that was effective use of social media time! Had totally forgotten about this webinar next Monday! Look forward to hearing from @[email protected] & @[email protected] #IDSky #ClinMicro #UTISky @[email protected]

RE: https://bsky.app/profile/did:plc:iuu7h4phnqvxwkiv36wbu4ll/post/3mgakcgctmc2w