"Among 5121 participants assessed, 1573 (30.7%) underwent DOC, of which 1502 (95.5%) were delabeled." - that's a lot of penicillin allergy mislabelling out there! 😲 However... DOC.. more likely to be prescribed penicillin and less likely WHO “Watch” or “Reserve” antibiotics #IDSky #ClinMicro #AMR

Direct Oral Challenge for Peni...
Direct Oral Challenge for Penicillin Allergy: A Hospital Implementation Evaluation Via the International Network of Antibiotic Allergy Nations (iNAAN) Study

Abstract. In this international, multicenter prospective study, implementing penicillin direct oral challenge (DOC) using a digital toolkit was acceptable,

OUP Academic
This is wild! (please excuse pun) Large, randomized study showing that Wolbachia‑based Aedes mosquito population suppression alone can significantly reduce dengue infections in a real‑world, dense urban setting! #dengue #IDSky #singapore @[email protected] #MedSky

Dengue Suppression by Male Wol...
Epithelial host pathogen interactions are complex! Happy to have contributed to this work, showing how mutations in Streptococcus pneumoniae biosynthesis genes results in divergent phenotyoic effects and host transcriptional responses (the bit I did!) #IDSky #immunosky @[email protected]

Disease-Attenuated Pneumococca...
Disease-Attenuated Pneumococcal Biosynthesis Gene Mutants Invade the Mucosal Epithelium and Induce Innate Immunity

Mutations in Streptococcus pneumoniae biosynthesis genes had impacts on virulence, oxidative stress, and metabolism. Mutants retained their microinvasive a

OUP Academic
We do quite a lot of antibiotic self administration in OPAT. Massive win if it can be achieved - lower requirements on hospital / community nurses & big autonomy win for the patients and their families. #OPAT #IDSky #ClinMicro

RE: https://bsky.app/profile/did:plc:ihlofya6s7dijxbv242tjam6/post/3mhq73irnj22b
The Widal test drives typhoid over diagnosis and, by extension, unnecessary antibiotic prescriptions. Good piece in @[email protected] #IDSky #ClinMicro #AMR

The diagnostic void: how typho...
Wow, have never seen a case of thyroid aspergillosis!!! #IDSky

RE: https://bsky.app/profile/did:plc:ao7ykaoap23gbmrggv4ytobn/post/3mhihskl4pe2o
Very sad reminder of the importance of getting a travel history #IDSky www.bbc.co.uk/news/article...

Barnsley rabies death could ch...
Barnsley rabies death could change disease notification rules

Doctors treating Yvonne Ford struggled to diagnose her before being told about holiday dog scratch.

BBC News