Secrets of cell division revealed by cutting-edge imaging technique
A study by Fena Ochs, new Group Leader and Associate Professor at Biotech Research & Innovation Center (BRIC) University of Copenhagen, delves deep into the intricate world of cell division. The study, published in Science, sheds light on the role of cohesin, which is a crucial protein complex that helps to faithfully segregate genetic material during cell division.
#Cohesin can resolve sister #chromatids already in G2 phase independent of #condensin - suggesting DNA #loopextrusion as generic mechanism for segregating #replicated genomes shared across different Structural Maintenance of #Chromosomes (SMC) protein complexes
Paul Batty, Daniel Gerlich et al #viennabiocenter
https://www.embopress.org/doi/10.15252/embj.2023113475
Researchers provide proof of the helical coiling of condensed chromosomes
The iconic X-shaped organization of metaphase chromosomes is frequently presented in textbooks and other media. The drawings explain in captivating manner that the majority of genetic information is stored in chromosomes, which transmit it to the next generation. "These presentations suggest that the chromosome ultrastructure is well-understood. However, this is not the case," says Dr. Veit Schubert from IPK's chromosome structure and function research group.
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The EMBO Journal