"Men tend to lose the Y chromosome from their cells as they age. But because the Y bears few genes other than for male determination, it was thought this loss would not affect health.

But evidence has mounted over the past few years that when people who have a Y chromosome lose it, the loss is associated with serious diseases throughout the body, contributing to a shorter lifespan."

https://theconversation.com/men-lose-their-y-chromosome-as-they-age-scientists-thought-it-didnt-matter-but-now-were-learning-more-275823

#Chromosomes #YChromosome #Health #Genetics

Men lose their Y chromosome as they age. Scientists thought it didn’t matter – but now we’re learning more

The Y chromosome doesn’t seem to do much except determine sex – but its loss in older men might be linked to heart disease, cancer and Alzheimer’s.

The Conversation
Bayesian data driven modelling of kinetochore dynamics: Space-time organisation of the human metaphase plate
https://atlas.whatip.xyz/post.php?slug=bayesian-data-driven-modelling-of-kinetochore-dynamics-space-time-organisation-of-the-human-metaphase-plate
Author summary Cell division segregates newly duplicated chromosomes into two daughter cells
#chromosomes #kinetochore #modelling #bayesian
Bayesian data driven modelling of kinetochore dynamics: Space-time organisation of the human metaphase plate

Author summary Cell division segregates newly duplicated chromosomes into two daughter cells. This is a mechanical process orchestrated by the mitotic spindle, a self-assembling molecular machine comp...

Scientists fuse human cells with #Plant #Protoplasts in laboratories to study how #Chromosomes function across vastly different species.

These #Hybrids cannot develop into organisms but offer vital clues about the fundamental evolution of life on Earth.

https://knowledgezone.co.in/posts/Human-Plant-Hybrid-Cells-695b82deb87924710cf7be36

XY Chromosomes Can Appear Female - Carole Hooven and Peter Attia

#chromosomes

#KnowledgeBit: #Karyogram is a diagram or #Photograph of the #Chromosomes of a cell, arranged in homologous pairs and in a numbered sequence. The way chromosomes are organized in the image makes them easy to visualize.

It is also called #Idiogram.

https://knowledgezone.co.in/kbits/64e87587d8188cdf1f403b4f

Before #cells can divide, they first need to replicate all of their #chromosomes, so that each of the daughter cells can receive a full set of #genetic material. Until now, scientists had believed that as division occurs, the #genome loses the distinctive 3D internal structure that it typically forms.
#Biomolecular #Biochemistry #Bioengineering #sflorg
https://www.sflorg.com/2025/10/bmol10172501.html
In a surprising discovery, scientists find tiny loops in the genomes of dividing cells

Enabled by a new high-resolution mapping technique, the findings overturn a long-held belief that the genome loses its 3D structure when cells divide.

AMP just published!
"A Complex Case of Koolen-De Vries Syndrome Associated with Hypopituitarism and Type 1 Diabetes Mellitus"

A Case Report by Mafalda Félix Cabral, Francisco Branco Caetano, Carla Conceição, Diana Antunes and Lurdes Lopes – A work from Unidade Local de Saúde São José, in Lisbon.

Full paper here:
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/22709

#multipleabnormalities #chromosomes #diabetesmellitus #hypopituitarism #intellectualdisability #genetics #actamedicaportuguesa

Why do #women outlive #men? A study of 1,176 species points to an answer.
Body of evidence suggests women's #longevity may derive, from having double X #chromosomes, a redundancy that protects them against harmful mutations. The most sweeping analysis to date of #lifespan differences between males and females in more than 1,000 #mammal and #bird species.
“From a #human standpoint, it’s really remarkable that women live longer across almost every country in the world”
https://www.msn.com/en-us/news/technology/why-do-women-outlive-men-a-study-of-1176-species-points-to-an-answer/ar-AA1NGK38
MSN