Lê Fê is backReading ET and feeling a bit of inauthenticiy from how they describe the missing heritability problem. The numeric solution seems to be there, as per Yango height papers, the mechanistic gap is an area of active investigation. Though not as well funded than the shiny new gwas, but it is there. He is a pessimist in areas showing clear progress? Matthews, Lucas J., and Eric Turkheimer. “Three Legs of the Missing Heritability Problem.” https://doi.org/10.1016/j.shpsa.2022.04.004. #behaviorgenetics
Joining #bga tomorrow. Funny that I am the single researcher working in #behaviorgenetics at #mastodon. I quick hashtag search showed nothing.
Right now it reads as a targeted attack to a specific project, more than a reasoned argument against small genetic designs. That's it folks, we will now start reading that only biobanks are worth funding (or I guess large twin studies too? Based on Eric's own work). In any case this is not the typical PPP paper. #behaviorgenetics @awaisaftab
After many years attending the Boulder workshop, I will be faculty. My session will cover mendelian randomization using twins. The mrdoc and mrdoc2 models. @[email protected] Statistical Genetics Workshop | Institute for Behavioral Genetics | University of Colorado Boulder https://www.colorado.edu/ibg/workshop. #behaviorgenetics
https://polygenicscores.org/explained/ A nice explainer on polygenic scores! #genetics #behaviorgenetics
Last pre print : https://www.researchsquare.com/article/rs-3411642/v1 #behaviorgenetics
Power, measurement error, and pleiotropy robustness in twin-design extensions to Mendelian Randomization
Mendelian Randomization (MR) has become an important tool for causal inference in the health sciences. It takes advantage of the random segregation of alleles to control for background confounding factors. In brief, the method works by using genetic variants as instrumental variables, but it d...
Franck Ramus (compte inactif)A 3-year #PhD or a 2-year #postdoc-toral position is available to do research with Dr Franck Ramus on Gene-environment interplay on #reading ability, #disability, and recovery, at the Department of Cognitive Studies, Ecole Normale Supérieure-PSL University, Paris, France.
#behaviorgenetics #dyslexia
More details here:
https://lscp.dec.ens.fr/en/job/gene-environment-interplay-reading-ability-disability-and-recovery-17398
#behaviorgenetics #dyslexia
More details here:
https://lscp.dec.ens.fr/en/job/gene-environment-interplay-reading-ability-disability-and-recovery-17398
Do I need relatedness pruning in the target data set while calculating a PRS, given I will use it in twin analysis? #genetics #prs #twins #behaviorgenetics