Recent research shows that antibiotics are accumulating in a major Brazilian river and the fish population, especially during the dry season when #pollution becomes more concentrated. Scientists even detected a banned drug inside fish sold for food, raising concerns about human exposure. Low levels of antibiotics are a relevant risk for creating #antibioticresistance amongst micro organisms in #ecosystems . A service we do not want.
#foodsafetyrisk

https://www.sciencedaily.com/releases/2026/03/260321012638.htm

MrkA enhances the virulence phenotype of #carbapenem -resistant #Klebsiella pneumoniae both in vitro & in vivo.

MrkA drives CRKP virulence by linking iron uptake, adhesion & carbon metabolism, with deletion sharply reducing pathogenicity.

#OpenAccess #antibioticresistance #microbiology

https://davidojcius.blogspot.com/2026/03/mrka-enhances-virulence-phenotype-of.html

Is antibacterial or regular hand soap best for killing germs?

Cleaning up our disinfectants: usage of antimicrobial biocides in direct-to-consumer products in Australia Open Access

"In supermarkets and chemists worldwide, consumers are faced with an array of antimicrobial domestic cleaning and personal hygiene products purporting to kill germs and keep people safe. Many of these proven active ingredients (biocides) encourage the development of antimicrobial resistance (AMR) in microbes and microbial populations, in turn increasing the likelihood of AMR infections. In order to understand and address the selective pressure towards AMR posed by the unrestricted use of biocides, it is necessary to understand which biocides are most frequently found in consumer products and the current regulatory framework that governs their use. In this research we survey the biocidal active ingredients in the major categories of cleaning and personal care products available from supermarkets and pharmacies in Australia, and comment on the regulations that dictate how these products are tested and marketed. Benzalkonium chloride and ethanol were the two most prevalent antimicrobial biocides in this study, while triclosan, which is banned in several jurisdictions, was found in a small number of products. In Australia, many antimicrobial consumer products are regulated for efficacy and safety under the Therapeutic Goods Act, but the potential to drive microbial adaptation and AMR is not considered. Overall this survey underscores the broad use and light regulation of antimicrobial biocides in products available to the general public in Australia, and provides an information resource to inform further research and stewardship efforts." >>
https://www.microbiologyresearch.org/content/journal/acmi/10.1099/acmi.0.000714.v3

#pathogens #handwashing #culture #HygieneProducts #biocide #disinfectant #antiseptic #AntimicrobialResistance #AntibioticResistance #fragrance #allergy #FragranceFree #perfume

Is antibacterial or regular hand soap best for killing germs?

Washing hands after using the toilet or patting a dog before a meal is crucial to remove feces-borne bacteria and germs. After COVID the message got through to most people. When one is in town looking for a public amenity or a cafe toilet, it is rare to find hot water, hand soap and a clean (paper) towel. But there is always a toilet spray in 1001 fragrance varieties.

In the absence of the ingredients for basic hand hygiene there is always a free plastic bottle of hand sanitizer since the last pandemic. Staff at grocers, bakers and cafes copiously cover their hands in the "antibacterial" and "antiseptic" products. Every product or packaging absorbs the persistent fragrance of the bought items and travels back into the home. The cost-effective chemical 'solution' does not substitute for hot water, soap and a towel.

"Professor Griffin says products claiming to kill bacteria are "not necessarily substantiated as being any better than just usual soap and water would be...These additives can be harsh and lead to dryness and cracked skin, which can create a pathway for germs to enter the body."

'Regular hand soap is very effective in removing potentially harmful pathogens (bacteria, viruses, fungi, and parasites), according to our experts. So, using that water, soap and that pneumatic action to get all of the dirt and grime from your hands and then rinsing is going to be more than adequate to keep you healthy."

"Our experts say there have also been studies suggesting that the use of soaps with antimicrobial additives can contribute to antibiotic resistance, which is problematic." >>
https://www.abc.net.au/news/2026-03-18/antibacterial-versus-normal-hand-soap-preventing-illness/106462854

#pathogens #handwashing #culture #HygieneProducts #biocide #disinfectant #antiseptic #AntimicrobialResistance #AntibioticResistance #fragrance #allergy #FragranceFree #perfume

Image: Fumbling dogs before lunch, Bellingen

Therapeutic challenges & Emerging Strategies against #Carbapenem -Resistant #Acinetobacter baumannii.

Emerging agents like sulbactam‑durlobactam, eravacycline & cefiderocol offer new options against multifaceted CRAB resistance.

https://davidojcius.blogspot.com/2026/03/therapeutic-challenges-and-emerging.html

#OpenAccess #microbiology #antibioticresistance

What do doctors prioritize when choosing #antibiotics for common infections?

In 756 doctors who recently treated UTIs etc.
- fast symptom relief and convenient dosing mattered most.
- #AntibioticResistance mattered least.

Corrected URL/DOI: https://doi.org/10.1093/ofid/ofaf783

#medicine #pharmacy #healthcare #AMR

Researchers built a miniature human bladder to demonstrate how the composition of urine weakens bladder tissue, promoting the recurrence of infections even after the use of antibiotics.

Read more: https://omniletters.com/human-mini-bladder-reveals-mechanism-that-promotes-recurrent-urinary-tract-infections/

#Science #MedicalResearch #Bioengineering #HumanBiology #UTI #UrinaryTractInfection #Microbiology #AntibioticResistance #PublicHealth #HealthcareInnovation

Ancient Superbug Found in Ice Shows Resistance to Modern Antibiotics

A 5,000-year-old bug found in ice can fight 10 modern medicines. This shows resistance is an old problem, not just new.

#Superbug, #AntibioticResistance, #AncientMicrobes, #Science, #Health

https://newsletter.tf/old-superbug-ice-resistance-drugs/

Scientists found a very old germ, 5,000 years old, in ice. This germ can fight against 10 kinds of medicine we use today. This discovery helps us understand how germs become strong against drugs over a long time.

#Superbug, #AntibioticResistance, #AncientMicrobes, #Science, #Health

https://newsletter.tf/old-superbug-ice-resistance-drugs/