Antibiotic resistance among germs swells during droughts, study suggests https://arstechnica.com/health/2026/03/antibiotic-resistance-among-germs-swells-during-droughts-study-suggests/

#environment #drought #health #AntibioticResistance

🦠 Could algorithms help us outpace evolving superbugs?

🔗 Antibacterial Drug Discovery: Deep Learning Successes and Challenges through the Structural Biology Lens. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0008

📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

#AntibioticResistance #DrugDiscovery #ComputationalBiology #StructuralBiology #MachineLearning #Bioinformatics

#AntibioticResistance

"Ancient bacteria, trapped in caves for millions of years, live in a miniature world of terror. Their only food source is each other. The survival tactics they develop make them resistant to almost all antibiotics. Now scientists hope to use their tricks to inspire new drugs and treatments.

Deep underground, plunging 1604ft (489m) beneath the Chihuahuan Desert in southern New Mexico, lies the Lechuguilla Cave, a cavern which stretches on for 149 miles (240km). There is no light, and little to eat either. Any living thing must eke out an existence under conditions of near starvation."

https://www.bbc.com/future/article/20260318-the-deep-cave-bacteria-resistant-to-modern-medicine

Drought Leads to Increased Antibiotic-Resistant Microbes in Soils

A new Caltech study indicates that drought increases the abundances of antibiotic-resistant microorganisms in soils, which directly correlates with an increase in antibiotic-resistant infections in hospitals. In other words, regions experiencing high aridity—hotter, drier regions—also experience higher levels of antibiotic-resistant infections. The work demonstrates the interconnectedness of climate, environment, and human health.

#AntibioticResistance #drought #AntibioticResistantMicrobe #soil #infection

https://www.caltech.edu/about/news/drought-leads-to-increased-antibiotic-resistant-microbes-in-soils

Recent research shows that antibiotics are accumulating in a major Brazilian river and the fish population, especially during the dry season when #pollution becomes more concentrated. Scientists even detected a banned drug inside fish sold for food, raising concerns about human exposure. Low levels of antibiotics are a relevant risk for creating #antibioticresistance amongst micro organisms in #ecosystems . A service we do not want.
#foodsafetyrisk

https://www.sciencedaily.com/releases/2026/03/260321012638.htm

MrkA enhances the virulence phenotype of #carbapenem -resistant #Klebsiella pneumoniae both in vitro & in vivo.

MrkA drives CRKP virulence by linking iron uptake, adhesion & carbon metabolism, with deletion sharply reducing pathogenicity.

#OpenAccess #antibioticresistance #microbiology

https://davidojcius.blogspot.com/2026/03/mrka-enhances-virulence-phenotype-of.html