Daniel MietchenUser benefits of #uniprot are estimated to be on the order of 20 times higher than operational costs https://www.sib.swiss/news/uniprot-user-benefits-up-to-39-times-higher-than-operational-costs
Jerven#UniProt The largest open+free #knowledgegraph in the life sciences. I will be talking about the why and the use cases at #semantics2025 5th of September 2025. Looking forward to seeing you all there!
https://2025-eu.semantics.cc/page/sessions?page=1nZsC6p2V3Yk73axR9Jl1NWq1IhVpkqtN
The OpenAIRE Graph#Update! Version 10.5.0 is live.
Featuring increases in the number of #Research products and affiliations, as well as updated mapping to import BioEntities from #ProteinDataBank and #ResearchData from #UniProt.
See all updates in the changelog!
Changelog https://graph.openaire.eu/changelog
#ScholarlyKnowledgeGraph #ScientificKnowledgeGraph #SKG #OpenData #OpenScience
Featuring increases in the number of #Research products and affiliations, as well as updated mapping to import BioEntities from #ProteinDataBank and #ResearchData from #UniProt.
See all updates in the changelog!
Changelog https://graph.openaire.eu/changelog
#ScholarlyKnowledgeGraph #ScientificKnowledgeGraph #SKG #OpenData #OpenScience
Peter CockInteresting in his #ISMBECCB2025 keynote that Amos Bairoch described as the worst decision of his career: caving to USA pressure to switch from funding model of free to academics & non-profits to use #SwissProt / #UniProt (with no login barrier), but paid access to Industry - to a free-to-all model funded by an NIH grant.
[I suspect industry lobbying at NIH there. One issue with grants is they are typically fixed term. Also, this would have been a very strong precedent for other DBs to follow - would have been more sustainable ecosystem?]
Darren#uniprot just hides the controls.. so you can't even try to full screen. but you can fortunately link out the #ebi #alphafold site where (ctd..)
CSBJ๐งฌ How do AlphaFold2 and ESMFold stack up when it comes to functional annotation?
๐ AlphaFold2 and ESMFold: A large-scale pairwise model comparison of human enzymes upon Pfam functional annotation. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.01.008
๐ CSBJ: https://www.csbj.org/
#AlphaFold2 #ESMFold #AIinScience #ProteinStructure #Enzymes #Pfam #UniProt #AlphaFold #HumanProteome #FunctionalAnnotation #AIinBiology #ComputationalBiology #FunctionalGenomics
Int Soc BiocurationIn 2023, ISB members voted to award Sandra Orchard the Exceptional Contribution to Biocuration award (https://www.biocuration.org/pascale-gaudet-and-sandra-orchard-recipients-of-the-2023-exceptional-contribution-to-biocuration-award).
Today at #biocuration2025 in Kansas City, she's presenting her award talk "How will the role of the Biocurator change in this world of Artificial Intelligence and Machine-Learning?" with a focus on current work at UniProt
At @swat4hcls there was a presentation by @albdrg that I really like: https://www.youtube.com/watch?v=F4Nl-nmLZA4 This uses #SPARQL to combine data in a privacy aware #beacons-api and combine it with public #knowledgegraph like #uniprot by @SIB and #wikidata @wikidata to reduce cost of the data integration challenge required to answer clinical question.
Semantic Beacons: a framework to support federated querying over genomic variants
Luis FalconSlide from my talk "Open Science for Medicine and Society" at Komazawa university. Using GNU Health to select a BRCA1 variant involved in breast #cancer and the 3D representation of the BRCT domain using PyMOL.
Having access to the latest scientific evidence makes a huge difference in patients, yet medical research is being dismantled by #corporatocracy.
Medicine and society evolves not because of the bullshit hype of AI, but because of the effort and talent of the men and women behind these projects. Respect
๐ฉบ
#UniProt #HUGO #GNUHealth #PyMOL #NIH #genomics #OpenScience
Having access to the latest scientific evidence makes a huge difference in patients, yet medical research is being dismantled by #corporatocracy.
Medicine and society evolves not because of the bullshit hype of AI, but because of the effort and talent of the men and women behind these projects. Respect
๐ฉบ #UniProt #HUGO #GNUHealth #PyMOL #NIH #genomics #OpenScience
c4r510My #SPARQL query of the day: List all known organisms in the #uniprot taxonomy database for which the donor of a sample depicted in #OMERO
is a host. Promptly answered
by federating local #OMERO Virtual Knowledge Graph and https://sparql.uniprot.org/sparql. I love it. CC: @nfdi4bioimage @joshmoore #NFDIrocks.
is a host. Promptly answered
by federating local #OMERO Virtual Knowledge Graph and https://sparql.uniprot.org/sparql. I love it. CC: @nfdi4bioimage @joshmoore #NFDIrocks.
