Journal of Experimental BotanyOct 4, 2023

Blossom-end rot causes black patches in fleshy fruits like #aubergine, tomato and #pepper πŸ† πŸ… πŸ«‘

This paper looks at a #starch-deficient #tomato mutant which is particularly #resistant to this, with only minor effects on #fruit size and #ripening - wow!

https://doi.org/10.1093/jxb/erad212

#TranscriptionalReprogramming #pyrophosphorylase #BlossomEndRot, #Carbohydrate #lipid #Solanum #fruit #development, #metabolism #stress

Starch deficiency in tomato causes transcriptional reprogramming that modulates fruit development, metabolism, and stress responses

Tomato fruit with disrupted starch biosynthesis undergo an important transcriptional and metabolic remodeling that affects central carbohydrate and lipid metabo

OUP Academic
Zoomers of the Sunshine Coast πŸ‡¨πŸ‡¦Dec 30, 2022

NATURE β€’ DEC 26, 2022

Transcriptional reprogramming from innate immune functions to a pro-thrombotic signature by monocytes in COVID-19

#Covid19 #TranscriptionalReprogramming

https://www.nature.com/articles/s41467-022-35638-y

Transcriptional reprogramming from innate immune functions to a pro-thrombotic signature by monocytes in COVID-19 - Nature Communications

Although myeloid cell dysfunction has been observed in COVID-19, the underlying mechanisms remain incompletely understood. Here, the authors demonstrate that monocytes from patients with mild to moderate COVID-19 show a blunted innate immune response and a pro-thrombotic signature following secondary SARS-CoV-2 challenge.

Nature