Hugues AbrielMar 30, 2023
#channelopathies #ionchannels #TRPM4
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RT @biorxivpreprint
Amino acid substitution in the S1 or CH1-CH2 linker domain of TRPM4: Two new TRPM4 variants found in complete heart block patients lead to gain of expression and gain of current https://biorxiv.org/cgi/content/short/2023.03.29.534743v1 #bioRxiv
https://twitter.com/biorxivpreprint/status/1641264045930995714
Hugues AbrielFeb 19, 2023

Boukenna (1st 1st authorship) et al. paper is now online - "Multiomics uncover the pro-inflammatory role of #Trpm4 deletion after myocardial infarction in mice" -> Loss of the #TRPchanel TRPM4 increases cardiac fibrosis post #MyocardialInfarction.

https://journals.physiology.org/doi/abs/10.1152/ajpheart.00671.2022#

Hugues AbrielFeb 17, 2023
A new scientist is born! Varjany Vashanthakumar (biomedical master's student @uniofbern @unil) gave a fantastic short talk (her first!) at the @LS2Switzerland @LS2_ICMT symposium on #IonChannels #TRPM4 #Channelopathies. Best of luck with your next goal, dear Varjany!