Myocardial infarction (MI) boosts cardiac AAV transduction.

🧬 Increased AAV gene delivery post-MI.
⏳ Peak at day 3 post-MI.
♻️ Independent of AAV dosage/serotypes.
🔬 Harnessing MI boosts gene therapy for heart conditions.

#MyocardialInfarction #GeneTherapy #AAV #CardiovascularResearch #Pub2Post

https://tnyp.me/VJ61sNPM/m

That first week back home after a heart attack… it can be a strange one. I’ve had patients tell me it’s like the world is suddenly muffled, or too loud, all at once. #cardiacrehabilitation #heartattackrecovery #hearthealthydiet #myocardialinfarction #preventingheartattack

https://priya.health/heart-attack-recovery/

Mastering Heart Attack Recovery: Steps to a Stronger You

Learn about heart attack recovery, including timelines, what to expect, lifestyle changes, and how to prevent a second heart attack. Expert advice for your journey.

Health With Priya

What is coronary angiography?
Coronary angiography is a method of examining the coronary arteries.

A radiopaque agent is injected into each coronary artery after the catheter has been inserted into the aorta.

The examination is done on an empty stomach.

The duration of the procedure is 20-90 minutes.

Some patients may experience allergic reactions to the injected chemical.

#angiography #coronary #Coronaryangiography #myocardialinfarction

I’ve been infected with SARS-CoV-2 once I know of from June 2022 on:
the cause of the long covid that now defines my daily existence.
I suspect once more in March or April 2020 — but of fucking course, at that time the public could not access covid tests!

Every ignorant person who asserts they’ve never had it
could have been ASYMPTOMATIC
(that they noticed / wanted to notice / were in a position to consider it amid whatever went on in their lives at the time).

Absolutely no one can say they were never infected unless they were a
complete 24/7 no-cheat hermit
and / or covid testing
correctly at least once daily, *every single morning* from November 2020 to now.

And guess what else?
The (rapid lateral flow) antigen tests probably haven’t been updated to the latest strains in a while.

Good luck if you do have Covid 19 but can’t get time off work!
The (possibly expired) disposable test may not pick up new strains as reliably as older ones, which won’t be circulating as much as newer ones.

#covid #covid19 #pandemic #lockdown #LongCovidKids #longCovid #longHaulers #cardiovascular #CVD #heart #heartDisease #pulmonary #heartAttack #myocardialinfarction #etiology #transmission #infection #disease #CDC #NHS

I have just read an article advocating for a higher #troponin threshold for rule-out of #MyocardialInfarction in #EmergencyDepartment patients (https://www.hindawi.com/journals/emi/2024/2241528/). The paper makes the mistake of using #NegativePredictiveValue rather the #Sensitivity for assessing algorithm safety. Consequently, they advocate for a threshold that would miss 1 in 25 #MI.
The journal does not allow letters to the editor, so I have included one here.
#EmergencyRoom
For #ED, #Cardiology, & #biochemistry colleagues. Just published in #ClinicalChemistry we show that the precision with which we measure #troponin concentrations can be quite poor at the low end without adversely affecting safety of diagnostic pathways to rule-out #MyocardialInfarction.
https://academic.oup.com/clinchem/advance-article-abstract/doi/10.1093/clinchem/hvae059/7665905?utm_source=advanceaccess&utm_campaign=clinchem&utm_medium=email
It also means the #FDA can relax their reporting restrictions to not <Limit of Quantitation (but will they?)
Determination of Clinically Acceptable Analytical Variation of Cardiac Troponin at Decision Thresholds

AbstractBackground. Clinical decision-making for risk stratification for possible myocardial infarction (MI) uses high-sensitivity cardiac troponin (hs-cTn

OUP Academic
Novo Nordisk's new Boston-area campus reflects 'competitive' R&D growth, and not just for GLP-1s—Myocardial Infarction: Three drug trials to watch in 2024—Pfizer's Abrysvo maintains strong efficacy through 2nd RSV season--http://bit.ly/w28kSd #novonordisk #boston #researchanddevelopment #myocardialinfarction #clinicaltrials #pfizer #rsv #vaccines #pharma #pharmanews #biotech #biopharma #biotechnology #cafepharma
Cafepharma

Cafepharma is a site for the pharmaceutical/medical industry. Our scope includes pharmaceutical, device, biotech, laboratory, animal health, dental, etc. We have curated daily news headlines, active forums where users can post anonymously, job listings and more.

Cafepharma

It’s just as you suspected: a lot of snow-shovelling might not be the best thing for you.

“… many people may face an increased risk of a heart attack or sudden cardiac arrest after shoveling heavy snow.”

https://newsroom.heart.org/news/snow-shoveling-can-be-hazardous-to-your-heart

#snow #cardiac #CardiacArrest #HeartAttack #MyocardialInfarction #winter

And yes, I am in the middle of a snowstorm! The amount of shovelling I plan to do is zero.

Snow shoveling can be hazardous to your heart

DALLAS, Dec. 15, 2022 — Clearing sidewalks and driveways of snow may be essential to keep from being shut in, however, the American Heart Association, the world’s leading nonprofit organization focused on heart and brain health for all, urges caution ...

American Heart Association
Troponin is NOT a marker of myocardial infarction #myocardialinfarction #health #shorts #troponin

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