Alice FrolovMar 6

⚗️ Molecular geometry is not just chemistry class. It determines drug activity, DNA stability, and enzyme function. Here is why shape is everything.

Molecular geometry is not abstract chemistry. It is the three-dimensional language that biology reads to decide what binds, what reacts, and what gets repaired.

💬 Which coordination geometry do you find most underappreciated in biological systems?

#Chemistry #MolecularBiology #StructuralChemistry #DrugDiscovery #AgingResearch #Longevity

Ilya Khodov LabAug 19, 2025
New paper out! 📄
We refined our single-NOESY method for bicalutamide in scCO₂.
Result: 24% open / 76% closed conformers — consistent with earlier work ✅ Robust methodology confirmed.
#NMR #NOESY #StructuralChemistry #DrugDesign
🔗 https://doi.org/10.1016/j.molstruc.2025.143449